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用于治疗肺栓塞的机械血栓切除术装置

Mechanical thrombectomy devices for the management of pulmonary embolism.

作者信息

Pandya Yash K, Tzeng Edith

机构信息

Division of Vascular Surgery, University of Pittsburgh Medical Center, Pittsburgh.

the School of Medicine, University of Pittsburgh, Pittsburgh.

出版信息

JVS Vasc Insights. 2024;2. doi: 10.1016/j.jvsvi.2024.100053. Epub 2024 Jan 11.

DOI:10.1016/j.jvsvi.2024.100053
PMID:39749259
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11695062/
Abstract

OBJECTIVE

The aim of this study was to review the most commonly used percutaneous mechanical thrombectomy devices for the treatment of pulmonary embolism today.

METHODS

A thorough search of the existing literature was conducted on commonly used percutaneous mechanical thrombectomy devices, most notably Inari Flowtriever, Penumbra's Indigo Aspiration, and Alphavac. Reported qualitative and quantitative information was abstracted and descriptively reviewed to ascertain the clinical utility and effectiveness of these devices.

RESULTS

Inari Flowtriever is one of the most frequently utilized thrombectomy devices with the most substantive industry-sponsored trial data. Penumbra's Indigo Aspiration is one of the up-and-coming devices that presents certain caveats in addition to the commonly utilized features of a percutaneous mechanical thrombectomy device, making it a viable alternative. Other newer devices such as Alphavac still lack substantial data, with some other lesser-known devices sporadically used and showing limited, primarily anecdotal evidence.

CONCLUSIONS

Each device has its positives and negatives. Data are growing on the clinical utility of these devices as their use is becoming more common. However, the long-term durability and overall cost-effectiveness remains to be determined. (JVS-Vascular Insights 2024;2:100053.).

摘要

目的

本研究旨在回顾当今治疗肺栓塞最常用的经皮机械血栓清除装置。

方法

对常用的经皮机械血栓清除装置,尤其是Inari Flowtriever、Penumbra的Indigo Aspiration和Alphavac,进行了全面的现有文献检索。提取报告的定性和定量信息并进行描述性综述,以确定这些装置的临床实用性和有效性。

结果

Inari Flowtriever是使用最频繁的血栓清除装置之一,有最丰富的行业资助试验数据。Penumbra的Indigo Aspiration是一种新兴装置,除了经皮机械血栓清除装置的常用功能外,还存在某些注意事项,使其成为一种可行的替代方案。其他较新的装置,如Alphavac,仍然缺乏大量数据,一些其他不太知名的装置偶尔使用,显示出有限的、主要是轶事性的证据。

结论

每种装置都有其优缺点。随着这些装置的使用越来越普遍,关于它们临床实用性的数据也在增加。然而,长期耐用性和总体成本效益仍有待确定。(《血管外科杂志-血管洞察》2024年;2:100053。)

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a634/11695062/5e85bacc3d35/nihms-2044457-f0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a634/11695062/d608ef9366bc/nihms-2044457-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a634/11695062/6a6cb8f0a8e4/nihms-2044457-f0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a634/11695062/5e85bacc3d35/nihms-2044457-f0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a634/11695062/d608ef9366bc/nihms-2044457-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a634/11695062/6a6cb8f0a8e4/nihms-2044457-f0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a634/11695062/5e85bacc3d35/nihms-2044457-f0003.jpg

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本文引用的文献

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Percutaneous endovascular vacuum assisted removal of intracardiac lesions using the AngioVac system: A real-world experience.使用AngioVac系统经皮血管内真空辅助清除心内病变:真实世界经验
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Outcomes in high-risk pulmonary embolism patients undergoing FlowTriever mechanical thrombectomy: the FLAME study in perspective.接受FlowTriever机械血栓切除术的高危肺栓塞患者的治疗结果:FLAME研究透视
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Percutaneous mechanical thrombectomy in a real-world pulmonary embolism population: Interim results of the FLASH registry.
真实世界肺栓塞人群中经皮机械血栓切除术:FLASH 登记研究的中期结果。
Catheter Cardiovasc Interv. 2022 Mar;99(4):1345-1355. doi: 10.1002/ccd.30091. Epub 2022 Feb 3.
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Submassive Pulmonary Embolism: Current Perspectives and Future Directions.亚大面积肺栓塞:当前观点与未来方向
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Randomized Trial Comparing Standard Versus Ultrasound-Assisted Thrombolysis for Submassive Pulmonary Embolism: The SUNSET sPE Trial.随机对照试验比较标准溶栓与超声辅助溶栓治疗亚大块肺栓塞:SUNSET sPE 试验。
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