Uehara Koichiro, Onuki Tatsuaki, Ishibashi Yukari, Matsunuma Sayuki, Ishida Hiroaki, Kumagai Jiro, Murakami Takayuki
Department of Urology Yokohama City Minato Red Cross Hospital Yokohama Kanagawa Japan.
Department of Pathology Yokohama City Minato Red Cross Hospital Yokohama Kanagawa Japan.
IJU Case Rep. 2024 Nov 4;8(1):56-59. doi: 10.1002/iju5.12809. eCollection 2025 Jan.
Local recurrence for upper tract urothelial carcinoma typically occurs within 2 years post-surgery. We report a rare case of retroperitoneal recurrence as squamous cell carcinoma 10 years after nephroureterectomy.
A 67-year-old female was referred to our urology department for a left ureteral tumor. The surgical specimen of the laparoscopic left nephroureterectomy revealed urothelial carcinoma at the pT3 stage. Ten years post-nephroureterectomy, magnetic resonance cholangiopancreatography revealed a mass lesion in the left retroperitoneum, a computed tomography-guided biopsy revealed squamous cell carcinoma. Despite suspected distant metastases of other organ tumors, examinations such as digestive endoscopy and bronchoscopy did not reveal any tumor lesions. The patient was diagnosed with recurrent invasive urothelial carcinoma as a pathological feature of squamous cell carcinoma.
The decision-making process for treating malignant tumors, such as in cases with recurrence as squamous cell carcinoma, can be challenging.
上尿路尿路上皮癌的局部复发通常发生在手术后2年内。我们报告一例罕见病例，在肾输尿管切除术后10年出现腹膜后复发，病理类型为鳞状细胞癌。
一名67岁女性因左侧输尿管肿瘤转诊至我院泌尿外科。腹腔镜下左侧肾输尿管切除术的手术标本显示为pT3期尿路上皮癌。肾输尿管切除术后10年，磁共振胰胆管造影显示左腹膜后有一肿块，计算机断层扫描引导下活检显示为鳞状细胞癌。尽管怀疑其他器官肿瘤有远处转移，但消化内镜和支气管镜等检查未发现任何肿瘤病变。该患者被诊断为复发性浸润性尿路上皮癌，病理特征为鳞状细胞癌。
对于鳞状细胞癌复发等恶性肿瘤的治疗决策过程可能具有挑战性。
