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蛇咬伤的临床流行病学研究:对尼泊尔东部一个社区治疗中心13年数据的审计

Clinico-epidemiological study of snakebite: an audit of 13 years of data from a community-based treatment centre in eastern Nepal.

作者信息

Manandhar Srista, Chhetri Sunit, Basnet Rohan, Gautam Arun, Bhattarai Urza, Uprety Manish, Sharma Aarjav, Gautam Ujwal, Bhushal Madhav, Sharma Sanjib Kumar

机构信息

Department of Internal Medicine, B.P. Koirala Institute of Health Sciences, Dharan 56700, Nepal.

KHDC Nepal, Dharan 56700, Nepal.

出版信息

Trans R Soc Trop Med Hyg. 2025 Jul 1;119(7):804-812. doi: 10.1093/trstmh/trae119.

Abstract

BACKGROUND

Snakebite envenomation is a global public health concern, especially in tropical and subtropical regions. We describe the demography, presentations, treatments and outcomes of snakebites from a community snakebite treatment centre in Nepal.

METHODS

This was a retrospective study of snakebite cases from 2008 to 2021 presenting in a community-based treatment centre in eastern Nepal. The data were collected from predesigned forms in the centre.

RESULTS

The median age of the victims (N=13 825) was 29 y (interquartile range 18-43) predominantly comprising farmers (39.5%). Cobras (Naja spp.) were the predominant species. Self-treatment practices like the application of tourniquets are common (74.5%) and antivenom was infused to 3.3% of victims. Motorcycles (57.9%) were the primary mode of transport, significantly reducing the time to reach healthcare centres compared with other means (p<0.001). The majority of patients visiting the community snakebite centre exhibited improvement (98.4%), with a low referral rate (0.6%) and case fatality rate (1.26%).

CONCLUSIONS

Snakebites are a common problem in rural Nepal. Neurotoxic envenomation, inflicted by the common cobra, predominates in this area. This community-based snakebite treatment centre, managed by paramedics, exemplifies the successful outcome of snakebite management in Nepal.

摘要

背景

蛇咬伤中毒是一个全球公共卫生问题,在热带和亚热带地区尤为突出。我们描述了尼泊尔一个社区蛇咬伤治疗中心的蛇咬伤患者的人口统计学特征、临床表现、治疗方法及治疗结果。

方法

这是一项对2008年至2021年在尼泊尔东部一个社区治疗中心就诊的蛇咬伤病例的回顾性研究。数据从该中心预先设计的表格中收集。

结果

受害者(n = 13825)的中位年龄为29岁(四分位间距18 - 43岁),主要为农民(39.5%)。眼镜蛇(眼镜蛇属)是主要的致伤蛇种。使用止血带等自我治疗方法很常见(74.5%),3.3%的受害者接受了抗蛇毒血清治疗。摩托车(57.9%)是主要的交通工具,与其他方式相比,显著缩短了到达医疗中心的时间(p < 0.001)。大多数到社区蛇咬伤中心就诊的患者病情有所改善(98.4%),转诊率低(0.6%),病死率为1.26%。

结论

蛇咬伤在尼泊尔农村是一个常见问题。该地区以普通眼镜蛇造成的神经毒性中毒为主。这个由护理人员管理的社区蛇咬伤治疗中心,体现了尼泊尔蛇咬伤治疗的成功成果。

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