O'Day J, Rotstein H, Weiner J M
Ophthalmology. 1985 Jan;92(1):109-13. doi: 10.1016/s0161-6420(85)34073-3.
A 40-year-old woman had documented mycosis fungoides of the skin. Over a period of five years, she had undergone intermittent treatment with psoralen long-wave ultraviolet light (PUVA) therapy. Despite regression of the skin lesions, tumor plaques developed in her eyelid and conjunctiva within the area shielded by dark glasses. Light and electron microscopic examination of a biopsy from the conjunctival plaque confirmed that the lesion was a deposit of mycosis fungoides. Local radiotherapy resulted in complete regression of these ocular lesions. The conjunctiva may well be an iatrogenic "sanctuary site" when this disease is treated with PUVA therapy.
一名40岁女性被诊断患有皮肤蕈样肉芽肿。在五年的时间里，她间断接受了补骨脂素长波紫外线（PUVA）治疗。尽管皮肤病变有所消退，但在她戴墨镜遮挡的区域内，眼睑和结膜出现了肿瘤斑块。对结膜斑块活检进行光镜和电镜检查证实，病变为蕈样肉芽肿沉积物。局部放疗使这些眼部病变完全消退。当用PUVA疗法治疗这种疾病时，结膜很可能是一个医源性“庇护所部位”。
