Zeng Hanling, Tang Shijie
Department of Plastic Surgery and Burns Center, Second Affiliated Hospital, Shantou University Medical College, Shantou, 515051, Guangdong, China.
Plastic Surgery Institute of Shantou University Medical College, Shantou, 515051, Guangdong, China.
Aesthetic Plast Surg. 2025 Jan 2. doi: 10.1007/s00266-024-04643-5.
Autologous fat injection has been proposed as a potential alternative to traditional rhinoplasty. However, the technique has been criticized for its disappointing retention and the potential complications associated with underfilling.
To summarize data on patient satisfaction, retention, complications and reinjection to provide a reference for fat injection for rhinoplasty.
Literature search was conducted on four databases (PubMed, Web of Science, Embase and Cochrane Library) using the keywords "rhinoplasty", "nasal tip", "nasal augmentation", "augmentation rhinoplasty", "revisional rhinoplasty" and "nasal revision" in conjunction with "fat", "lipofilling", "lipoinjection" and "adipose graft". Under eligibility criteria, two reviewers conducted an examination of each potential study.
Eleven studies with a total of 849 patients were included in the systematic review and all patients received at least one fat injection. In nine studies that evaluated patient satisfaction, a total of 820 patients exhibited an high satisfaction ranging from 63 to 100% (approximately 81.2%). Complications associated with fat injection are uncommon, with edema and bruising being the most frequently reported. Three studies measured fat retention, which were < 50% (at 6 months after injection), 44.54% (range 21-74%) (at 3 months after injection) and 50.5% ± 7.0% (at 6 months after injection). A minimum of 18.61% (158) of the 849 patients enrolled underwent one or more injections. At 1-year follow-up, the reinjection rate is at least 19.27%.
Autologous fat injection is safe and effective for rhinoplasty. The resorbability of fat requires additional injections in certain noses where deformities are evident.
This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .
自体脂肪注射已被提议作为传统隆鼻术的一种潜在替代方法。然而，该技术因脂肪留存率不尽人意以及与填充不足相关的潜在并发症而受到批评。
总结有关患者满意度、脂肪留存、并发症及再次注射的数据，为隆鼻脂肪注射提供参考。
在四个数据库（PubMed、Web of Science、Embase和Cochrane图书馆）中进行文献检索，使用关键词“隆鼻术”“鼻尖”“鼻整形”“隆鼻整形术”“修复性隆鼻术”“鼻修复术”，并结合“脂肪”“脂肪填充”“脂肪注射”和“脂肪移植”。在纳入标准下，两名评审员对每项潜在研究进行审查。
系统评价纳入了11项研究，共849例患者，所有患者均接受了至少一次脂肪注射。在9项评估患者满意度的研究中，共820例患者表现出较高满意度，范围为63%至100%（约81.2%）。与脂肪注射相关的并发症并不常见，最常报告的是水肿和瘀斑。三项研究测量了脂肪留存率，分别为注射后6个月时＜50%、注射后3个月时44.54%（范围21%-74%）以及注射后6个月时50.5%±7.0%。849例纳入患者中至少18.61%（158例）接受了一次或多次注射。在1年随访时，再次注射率至少为19.27%。
自体脂肪注射用于隆鼻安全有效。脂肪的可吸收性要求在某些畸形明显的鼻子中进行额外注射。
证据水平III：本刊要求作者为每篇文章指定证据水平。有关这些循证医学评级的完整描述，请参阅目录或作者在线指南www.springer.com/00266。
