Baghban Roghayyeh, Namvar Ehsan, Attar Alireza, Mortazavi Mojtaba
Poostchi Ophthalmology Research Center, Department of Ophthalmology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
Poostchi Ophthalmology Research Center, Department of Ophthalmology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
Biomed Pharmacother. 2025 Feb;183:117786. doi: 10.1016/j.biopha.2024.117786. Epub 2025 Jan 2.
The inherent limitations of traditional treatments for Diabetic Retinopathy (DR) have spurred the development of various nanotechnologies, offering a safer and more efficient approach to managing the disease. Nanomedicine platforms present promising advancements in the diagnosis and treatment of DR by enhancing imaging capabilities, enabling targeted and controlled drug delivery. These innovations ultimately lead to more effective and personalized treatments with fewer side effects. This review highlights the progress, challenges, and opportunities in developing effective diagnostics and therapeutics for DR. Additionally, it explores innovative engineering techniques that leverage our growing understanding of nano-bio interactions to create more potent nanotherapeutics for patients.
糖尿病视网膜病变（DR）传统治疗方法的固有局限性推动了各种纳米技术的发展，为该疾病的管理提供了一种更安全、更有效的方法。纳米医学平台通过增强成像能力、实现靶向和可控药物递送，在DR的诊断和治疗方面展现出了有前景的进展。这些创新最终带来更有效、更个性化且副作用更少的治疗。本综述重点介绍了在开发有效的DR诊断和治疗方法方面取得的进展、面临的挑战和机遇。此外，它还探讨了创新的工程技术，这些技术利用我们对纳米-生物相互作用日益深入的理解，为患者创造更有效的纳米疗法。
