Shan Eric, Xiong Ruiying, Katzman Michael, Ali Zarina, Lee Daniel, Delgado M Kit, Agarwal Anish
University of Pennsylvania, Philadelphia, Pennsylvania, USA
University of Pennsylvania, Philadelphia, Pennsylvania, USA.
BMJ Open Qual. 2025 Jan 2;14(1):e003040. doi: 10.1136/bmjoq-2024-003040.
Prescription opioids after surgery may pose a risk if left unused. However, prescribers rely on their best judgement in determining how much their patients need, often resulting in over-prescription of these medications. Opioid disposal is a strategy to reduce the risk of persistent use or misuse of opioids. At-home disposal kits allow patients to safely dispose of leftover opioids. In this study, we assess the impact of opioid disposal kits on disposal rates after orthopedic surgery. In a difference-in-differences study of 1,321 eligible patients, disposal kits were associated with a 10.6 percentage point increase (95% CI: -3.5% to 24.7%) in disposal rates as well as a 10.5 percentage point increase (95% CI: 0.2% to 20.9%) in the fraction of opioids disposed. We build on prior research and identify that providing surgery patients with an opioid disposal kit at the time of discharge increases their self-disposal rates.
术后未使用的处方阿片类药物可能会带来风险。然而，开处方者在确定患者所需剂量时依靠的是自己的最佳判断，这常常导致这些药物的过度处方。阿片类药物处置是一种降低阿片类药物持续使用或滥用风险的策略。家庭处置试剂盒使患者能够安全地处置剩余的阿片类药物。在本研究中，我们评估了阿片类药物处置试剂盒对骨科手术后处置率的影响。在一项针对1321名符合条件患者的双重差分研究中，处置试剂盒与处置率提高10.6个百分点（95%置信区间：-3.5%至24.7%）以及阿片类药物处置比例提高10.5个百分点（95%置信区间：0.2%至20.9%）相关。我们在先前研究的基础上，确定在出院时为手术患者提供阿片类药物处置试剂盒可提高他们的自我处置率。
