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OMERACT巨细胞动脉炎超声评分(OGUS)的可靠性:一项基于患者的、涉及血管超声专家和非专家的实践结果

Reliability of the OMERACT Giant cell arteritis Ultrasonography Score (OGUS): results of a patient-based exercise involving experts and non-experts in vascular ultrasonography.

作者信息

Duftner Christina, Redlinger Norbert, Bruyn George A, Chadachan Veerendra, Chrysidis Stavros, Correyero Maria, D'Agostino Maria Antonietta, Dalsgaard Nielsen Berit, Dasgupta Bhaskar, De Miguel Eugenio, Diamantopoulos Andreas P, Fulvio Giovanni, Gkikopoulos Nikitas, Hartung Wolfgang, Hocevar Alojzija, Keen Helen, Kurteva Vesselina, Mandl Peter, Manger Eva, Mercatelli Paolo, Midtgard Irina, Monti Sara, Muller Raili, Mykkänen Kati, Pineda Carlos, Ponte Cristina, Reffat Duriad, Sarbu Adela-Cristina, Seitz Luca, Terslev Lene, Schmidt Wolfgang A, Dejaco Christian

机构信息

Department of Internal Medicine, Clinical Division of Internal Medicine II, Medical University of Innsbruck, Innsbruck, Tirol, Austria

Department of Internal Medicine, Clinical Division of Internal Medicine II, Medical University of Innsbruck, Innsbruck, Tirol, Austria.

出版信息

RMD Open. 2025 Jan 2;11(1):e004667. doi: 10.1136/rmdopen-2024-004667.

DOI:10.1136/rmdopen-2024-004667
PMID:39753294
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11749318/
Abstract

OBJECTIVE

To test the reliability of the Outcome Measures in Rheumatology Giant cell arteritis (GCA) Ultrasonography Score (OGUS) and other composite scores in a patient-based exercise involving experts and non-experts in vascular ultrasonography.

METHODS

Six GCA patients were scanned twice (two rounds separated ≥3 hours) by 12 experts and 12 non-experts. Non-experts received 90 min of theoretical and 240 min of practical training between rounds 1 and 2. Ultrasonography was conducted on temporal arteries (common superficial, frontal and parietal branches) and axillary arteries bilaterally to calculate the OGUS, the Southend score and the Halo count. Inter-reader and intra-reader reliability were assessed by intraclass correlation coefficient (ICC).

RESULTS

Mean age of GCA patients was 78±5.1 years, 2 (33.3%) were women, and all were in clinical remission. Expert inter-reader ICC of the OGUS was 0.60 in both rounds, 0.40 in round 1 and 0.51 in round 2 for the Southend score and 0.45 and 0.52, respectively, for the Halo count. Median ICCs for intra-reader reliability were 0.86, 0.73 and 0.65 for the OGUS, Southend score and Halo count, respectively.For non-experts, inter-reader ICCs in round 1 were 0.20 for the OGUS, 0.20 for a normalised Southend score (=score divided by available segments) and 0.35 for a normalised Halo count. After training, inter-reader reliability ICCs improved to 0.52, 0.29 and 0.54, respectively.

CONCLUSION

Inter-reader reliability was fair to moderate, and intra-reader reliability was good for OGUS, Southend score and Halo count among experts. Inter-reader reliability of non-experts in vascular ultrasonography improved after the training.

摘要

目的

在一项涉及血管超声专家和非专家的患者实践活动中,检验风湿病巨细胞动脉炎(GCA)超声检查结果测量评分(OGUS)及其他综合评分的可靠性。

方法

12名专家和12名非专家对6例GCA患者进行两次扫描(两轮扫描间隔≥3小时)。非专家在第一轮和第二轮扫描之间接受了90分钟的理论培训和240分钟的实践培训。对双侧颞动脉(常见浅表、额支和顶支)和腋动脉进行超声检查,以计算OGUS、绍森德评分和晕环计数。通过组内相关系数(ICC)评估阅片者间和阅片者内的可靠性。

结果

GCA患者的平均年龄为78±5.1岁,2例(33.3%)为女性,所有患者均处于临床缓解期。OGUS阅片者间的专家ICC在两轮中均为0.60,绍森德评分在第一轮为0.40,第二轮为0.51,晕环计数分别为0.45和0.52。阅片者内可靠性的中位数ICC,OGUS为0.86,绍森德评分为0.73,晕环计数为0.65。对于非专家,第一轮阅片者间的ICC,OGUS为0.20,标准化绍森德评分(=评分除以可用节段数)为0.20,标准化晕环计数为0.35。培训后,阅片者间可靠性的ICC分别提高到0.52、0.29和0.54。

结论

阅片者间可靠性为中等,阅片者内可靠性对于专家而言,OGUS、绍森德评分和晕环计数良好。血管超声检查中非专家的阅片者间可靠性在培训后有所提高。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ddb/11749318/0b7497b6b6db/rmdopen-11-1-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ddb/11749318/0b7497b6b6db/rmdopen-11-1-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ddb/11749318/0b7497b6b6db/rmdopen-11-1-g001.jpg

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2
EULAR recommendations for the use of imaging in large vessel vasculitis in clinical practice: 2023 update.EULAR 临床实践中应用影像学诊断大血管血管炎的推荐:2023 年更新版。
Ann Rheum Dis. 2024 May 15;83(6):741-751. doi: 10.1136/ard-2023-224543.
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Measuring treatment outcomes and change in disease activity in giant cell arteritis: a systematic literature review informing the development of the EULAR-ACR response criteria on behalf of the EULAR-ACR response criteria in giant cell arteritis task force.
评估巨细胞动脉炎的治疗结局和疾病活动变化:一项系统文献回顾,代表巨细胞动脉炎 EULAR-ACR 反应标准工作组为 EULAR-ACR 反应标准的制定提供信息。
RMD Open. 2023 Jun;9(2). doi: 10.1136/rmdopen-2023-003233.
4
Disease stratification in GCA and PMR: state of the art and future perspectives.巨细胞动脉炎和 PMR 中的疾病分层:现状与未来展望。
Nat Rev Rheumatol. 2023 Jul;19(7):446-459. doi: 10.1038/s41584-023-00976-8. Epub 2023 Jun 12.
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Treat-to-target recommendations in giant cell arteritis and polymyalgia rheumatica.巨细胞动脉炎和风湿性多肌痛的靶向治疗建议。
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8
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