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中国在体外肝脏手术方面的特殊贡献。

Particular Chinese contributions to extracorporeal liver surgery.

作者信息

Aini Abudusalamu, Lu Qian, Wen Hao, Wang Wen-Tao, Aji Tuerganaili, Chen Zhi-Yu, Zhang Lei-Da, Yang Zhan-Yu, Yang Jia-Yin, Fan Hai-Ning, Wang Wei-Lin, Li Xiang-Cheng, Zhang Yu, Dong Jia-Hong

机构信息

Hepatopancreatobiliary Center, Organ Transplantation Center, Beijing Tsinghua Changgung Hospital, Tsinghua University, Beijing 102218, China; Key Laboratory of Digital Intelligence Hepatology (Chinese Ministry of Education), School of Clinical Medicine, Tsinghua University, Beijing 100084, China; Research Unit of Precision Hepatobiliary Surgery Paradigm, Chinese Academy of Medical Sciences, Beijing 100010, China; Institute for Organ Transplantation and Bionics, Institute for Precision Medicine, School of Clinical Medicine, Tsinghua University, Beijing 100010, China.

Hepatobiliary & Echinococcosis Surgery, Digestive & Vascular Surgery Center, The First Affiliated Hospital of Xinjiang Medical University, Urumqi 830054, China.

出版信息

Hepatobiliary Pancreat Dis Int. 2025 Feb;24(1):57-66. doi: 10.1016/j.hbpd.2024.12.005. Epub 2024 Dec 19.

Abstract

Extracorporeal liver surgery (ELS), also known as liver autotransplantation, is a hybrid (cross-fertilized) surgery incorporating the technical knowledge from extreme liver and transplant liver surgeries, and recently became more embraced and popularized among leading centers. ELS could be summarized into three major categories, namely, ex-situ liver resection and autotransplantation (ELRA), ante-situm liver resection and autotransplantation (ALRA) and auxiliary partial liver autotransplantation (APLA). The successful development of ELS during the past 37 years is definitely inseparable from continuous efforts done by Chinese surgeons and researchers. Especially, the precision liver surgery paradigm has allowed to transform ELS into a modularized, more simplified, and standardized surgery, to upgrade surgical skills, to improve peri-operative outcome and long-term survival, to increase the capability of surgeons to select more complex diseases and to expand the level of medical service to the population. This review highlights the Chinese contributions to the field of ELS, focusing thereby on features of different surgical types, technical innovations, disease selection and surgical indication, patient prognosis and future perspectives.

摘要

体外肝脏手术(ELS),也称为肝脏自体移植,是一种融合了极端肝脏手术和移植肝脏手术技术知识的混合(交叉融合)手术,最近在各大领先中心越来越受到青睐和推广。ELS可概括为三大类,即异位肝切除与自体移植(ELRA)、原位肝切除与自体移植(ALRA)以及辅助部分肝脏自体移植(APLA)。在过去37年里,ELS的成功发展无疑离不开中国外科医生和研究人员的持续努力。特别是,精准肝脏手术模式已使ELS转变为一种模块化、更简化和标准化的手术,提升了手术技能,改善了围手术期结果和长期生存率,增强了外科医生选择更复杂疾病的能力,并扩大了医疗服务水平。本综述重点介绍了中国在ELS领域的贡献,从而聚焦于不同手术类型的特点、技术创新、疾病选择和手术指征、患者预后及未来展望。

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