对纤维化和进行性肾损伤机制的见解。 - Suppr

Insights into the mechanisms of fibrosis and progressive kidney injury.

作者信息

Lamas Santiago, Ruiz-Ortega Marta

机构信息

Program of Physiological and Pathological Processes, Centro de Biología Molecular Severo Ochoa (CSIC-UAM), Madrid, Spain.

Cellular and Molecular Biology in Renal and Vascular Pathology Laboratory, Instituto de Investigación Sanitaria-Fundación Jiménez Díaz, Universidad Autónoma de Madrid, Madrid, Spain.

出版信息

Nat Rev Nephrol. 2025 Feb;21(2):79-80. doi: 10.1038/s41581-024-00922-1.

DOI:10.1038/s41581-024-00922-1

PMID:39753691

Abstract

摘要

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Insights into the mechanisms of fibrosis and progressive kidney injury.

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本文引用的文献

Metabolism at the crossroads of inflammation and fibrosis in chronic kidney disease.

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Single-cell multi-omic and spatial profiling of human kidneys implicates the fibrotic microenvironment in kidney disease progression.

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WWP2 Regulates Renal Fibrosis and the Metabolic Reprogramming of Profibrotic Myofibroblasts.

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Insights into the mechanisms of fibrosis and progressive kidney injury.

作者信息

Lamas Santiago, Ruiz-Ortega Marta

机构信息

Program of Physiological and Pathological Processes, Centro de Biología Molecular Severo Ochoa (CSIC-UAM), Madrid, Spain.

Cellular and Molecular Biology in Renal and Vascular Pathology Laboratory, Instituto de Investigación Sanitaria-Fundación Jiménez Díaz, Universidad Autónoma de Madrid, Madrid, Spain.