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精神药物:2021 - 2022年伊朗大不里士处方趋势的描述性研究

Psychotropic medications: a descriptive study of prescription trends in Tabriz, Iran, 2021-2022.

作者信息

Farahbakhsh Mostafa, Fakhari Ali, Azimian Ali, Khameneh Amin, Matinkia Mahsa, Aghajani Ehsan

机构信息

Research Center of Psychiatry and Behavioral Sciences, Tabriz University of Medical Sciences, Tabriz, Islamic Republic of Iran.

Tabriz University of Medical Sciences, Tabriz, Islamic Republic of Iran.

出版信息

BMC Psychiatry. 2025 Jan 3;25(1):10. doi: 10.1186/s12888-024-06451-2.

Abstract

INTRODUCTION

Mental disorders, such as anxiety and depression, significantly impacted global populations in 2019 and 2020, with COVID-19 causing a surge in prevalence. They affect 13.4% of the people worldwide, and 21% of Iranians have experienced them. Prescription analysis is critical for evaluating and improving medical care in a cost-effective manner. This study examined prescription patterns for psychotropic drugs in outpatient settings to improve the understanding of medication utilization in a variety of patients. It aimed to assist healthcare professionals in making well-informed decisions about drug prescriptions, a topic not much addressed in Iran.

METHOD

A descriptive study was conducted using data extracted from the Social Security Organization in Iran. We analyzed prescriptions in Tabriz from March 2021 to March 2022. Prescription data were categorized by medication category, physician specialty, age group, and sex. Then statistical analysis was performed using SPSS 2022.

RESULTS

We analyzed the number of psychotropic medication prescriptions issued by 7246 doctors to a group of 413,466 individuals over a year representing 44.9% of our target population. The average age of individuals receiving psychotropic drugs was 45.57 years. Gabapentin had the highest prescription rate, followed by sertraline. Antidepressants accounted for 38.1% of all prescriptions, with anxiolytics accounting for 18.6%. Other psychotropic drugs included alprazolam, chlordiazepoxide, and valproate. Adults in all age groups had the highest frequency of prescriptions for psychotropic medications. The majority of patients were female (63.5%). General practitioners had the highest number of instances of prescribing psychotropic drugs, with psychiatrists contributing 54.7% of the total prescriptions.

CONCLUSION

Approximately 45% of the target population received psychotropic medication, which highlights the significant prevalence of mental health issues in Iran. Antidepressants were the most commonly administered class, highlighting the need for training programs that specifically address their possible negative effects and the correct dosage. The goal is to provide healthcare practitioners with a comprehensive understanding of prescription trends, enabling them to administer the most appropriate treatments.

摘要

引言

焦虑和抑郁等精神障碍在2019年和2020年对全球人口产生了重大影响,新冠疫情导致其患病率激增。这些精神障碍影响着全球13.4%的人口,21%的伊朗人曾经历过这些问题。处方分析对于以具有成本效益的方式评估和改善医疗保健至关重要。本研究调查了门诊环境中精神药物的处方模式,以增进对各类患者用药情况的了解。其目的是帮助医疗保健专业人员在药物处方方面做出明智的决策,这一话题在伊朗尚未得到充分探讨。

方法

采用从伊朗社会保障组织提取的数据进行描述性研究。我们分析了大不里士2021年3月至2022年3月期间的处方。处方数据按药物类别、医生专业、年龄组和性别进行分类。然后使用SPSS 2022进行统计分析。

结果

我们分析了7246名医生在一年内向413466名个体开具的精神药物处方数量,这些个体占我们目标人群的44.9%。接受精神药物治疗的个体平均年龄为45.57岁。加巴喷丁的处方率最高,其次是舍曲林。抗抑郁药占所有处方的38.1%,抗焦虑药占18.6%。其他精神药物包括阿普唑仑、氯氮卓和丙戊酸盐。所有年龄组的成年人精神药物处方频率最高。大多数患者为女性(63.5%)。全科医生开具精神药物的次数最多,精神科医生开具的处方占总处方的54.7%。

结论

约45%的目标人群接受了精神药物治疗,这凸显了伊朗心理健康问题的高患病率。抗抑郁药是最常用的药物类别,这突出表明需要开展专门针对其可能的负面影响和正确剂量的培训项目。目标是让医疗保健从业者全面了解处方趋势,使其能够进行最合适的治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d56/11697799/27dfd1236c1f/12888_2024_6451_Str1_HTML.jpg

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