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耳内镜下湿耳状态对鼓膜修复术疗效的影响:一项前瞻性病例对照研究

Influence of the wet-ear state on the outcomes of tympanic membrane repair under ear endoscopy: a prospective case-control study.

作者信息

Zhang Jun, Bai Qinglin, Zhao Na, Li Cong, Yang Jia

机构信息

Department of Otolaryngology-Head and Neck Surgery, Zhangqiu People's Hospital, No.1920 Mingshui Huiquan Road, Zhangqiu Distict, Jinan, 250200, People's Republic of China.

Department of Anesthesia, Zhangqiu People's Hospital, Jinan, China.

出版信息

BMC Surg. 2025 Jan 3;25(1):2. doi: 10.1186/s12893-024-02714-7.

DOI:10.1186/s12893-024-02714-7
PMID:39754126
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11697829/
Abstract

BACKGROUND

To prospectively determine whether tympanoplasty for tympanic membrane perforation (TMP) in wet ears impacts recovery.

METHODS

We prospectively enrolled 32 TMP patients (2021-2023) and divided them into the wet-ear (14 patients) and dry-ear groups (18 patients), according to the presence of middle-ear secretions/edema. All patients underwent high-resolution thin-slice computed tomography, ear endoscopy, and pure tone audiometry.

RESULTS

Perforation healing was similar in the dry- ear (94.44%) and wet-ear groups (85.7%, P = 0.5685). At 3 months, dry ears were achieved in 94.44% and 92.86% of patients in the dry- and wet-ear groups, respectively (P > 0.05). The air-bone gap (ABG) at 3 months was similar in the dry-ear (9.4047 ± 4.3415 dB) and wet-ear groups (6.5278 ± 5.4552 dB, P = 0.1171). In both groups, the mean air-conduction threshold, bone-conduction threshold, and ABG significantly decreased postoperatively (P < 0.05).

CONCLUSION

Tympanoplasty for TMP in wet ears does not adversely affect healing.

摘要

背景

前瞻性地确定在中耳潮湿的情况下进行鼓膜穿孔(TMP)鼓室成形术是否会影响恢复。

方法

我们前瞻性纳入了32例TMP患者(2021 - 2023年),并根据中耳分泌物/水肿情况将他们分为中耳潮湿组(14例患者)和中耳干燥组(18例患者)。所有患者均接受了高分辨率薄层计算机断层扫描、耳内镜检查和纯音听力测定。

结果

中耳干燥组(94.44%)和中耳潮湿组(85.7%)的穿孔愈合情况相似(P = 0.5685)。3个月时,中耳干燥组和中耳潮湿组分别有94.44%和92.86%的患者中耳变干燥(P > 0.05)。3个月时,中耳干燥组(9.4047 ± 4.3415 dB)和中耳潮湿组(6.5278 ± 5.4552 dB)的气骨导间距(ABG)相似(P = 0.1171)。两组患者术后平均气导阈值、骨导阈值和ABG均显著降低(P < 0.05)。

结论

中耳潮湿情况下进行TMP鼓室成形术不会对愈合产生不利影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/866d/11697829/fca61fa5aeb1/12893_2024_2714_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/866d/11697829/f3885b19d540/12893_2024_2714_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/866d/11697829/da1d39701c4c/12893_2024_2714_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/866d/11697829/fca61fa5aeb1/12893_2024_2714_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/866d/11697829/f3885b19d540/12893_2024_2714_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/866d/11697829/da1d39701c4c/12893_2024_2714_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/866d/11697829/fca61fa5aeb1/12893_2024_2714_Fig3_HTML.jpg

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J Otolaryngol Head Neck Surg. 2024 Jan-Dec;53:19160216241267724. doi: 10.1177/19160216241267724.
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Tracking cell layer contribution during repair of the tympanic membrane.追踪细胞层在鼓膜修复过程中的贡献。
Dis Model Mech. 2024 Mar 1;17(3). doi: 10.1242/dmm.050466. Epub 2024 Mar 28.
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Chronic tympanic membrane perforation repair with a collagen-based scaffold: An in vivo model.
基于胶原的支架修复慢性鼓膜穿孔:一种体内模型。
Int J Pediatr Otorhinolaryngol. 2024 Jan;176:111807. doi: 10.1016/j.ijporl.2023.111807. Epub 2023 Dec 1.
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Epimorphic regeneration in the mammalian tympanic membrane.哺乳动物鼓膜的再生性再生
NPJ Regen Med. 2023 Oct 18;8(1):58. doi: 10.1038/s41536-023-00332-0.
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Outcomes of Tympanoplasty Performed in Dry and Wet Ear Groups: A Comprehensive Comparative Study.干耳组和湿耳组鼓室成形术的结果:一项综合比较研究。
Indian J Otolaryngol Head Neck Surg. 2022 Dec;74(Suppl 3):4164-4170. doi: 10.1007/s12070-021-02881-6. Epub 2021 Sep 30.
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[A prospective comparative study on the short-term effect of endoscopic myringoplasty in dry and wet ears].[内镜下鼓膜成形术对干耳和湿耳短期效果的前瞻性对比研究]
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2020 Oct;34(10):874-878. doi: 10.13201/j.issn.2096-7993.2020.10.003.
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