Yang Zheng, Zhang Meng, Du Chang
Guangdong Provincial Key Laboratory of Biotechnology for Plant Development, School of Life Science, South China Normal University, Guangzhou 510631, China; Zhengzhou Research Base, National Key Laboratory of Cotton Bio-breeding and Integrated Utilization, School of Agricultural Sciences, Zhengzhou University, Zhengzhou, Henan, 450001, China.
College of Agronomy, Northwest A&F University, Yangling, Shaanxi 712100, China.
Trends Plant Sci. 2025 Apr;30(4):347-349. doi: 10.1016/j.tplants.2024.12.010. Epub 2025 Jan 3.
Recently, Torres-Romero et al. identified a novel lipid droplet (LD)-associated protein, α/β-hydrolase domain containing protein 1 (ABHD1), in algae. Structurally, ABHD1 promotes the budding and growth of LDs and, functionally, it hydrolyzes lyso-diacylglyceryl-N,N,N-trimethylhomoserine (lyso-DGTS) to generate glyceryl-N,N,N-trimethylhomoserine (GTS) and free fatty acids (FFAs). Taken together, ABHD1 mediates a novel pathway for LD formation.
最近，托雷斯 - 罗梅罗等人在藻类中鉴定出一种新的与脂滴（LD）相关的蛋白质，即含α/β水解酶结构域蛋白1（ABHD1）。在结构上，ABHD1促进脂滴的出芽和生长，在功能上，它水解溶血二酰基甘油 - N，N，N - 三甲基高丝氨酸（溶血 - DGTS）以生成甘油 - N，N，N - 三甲基高丝氨酸（GTS）和游离脂肪酸（FFA）。综上所述，ABHD1介导了一种新的脂滴形成途径。
