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1型糖尿病患者与非1型糖尿病患者的饮食失调:基于全国人群队列的发病率及治疗情况

Eating disorders among people with and without type 1 diabetes: incidence and treatment in a nationwide population-based cohort.

作者信息

Hirvelä Leon, Haukka Jari, Keski-Rahkonen Anna, Sipilä Pyry N

机构信息

Department of Public Health, University of Helsinki, Helsinki, Finland.

出版信息

Diabetologia. 2025 Apr;68(4):766-777. doi: 10.1007/s00125-024-06346-7. Epub 2025 Jan 4.

Abstract

AIMS/HYPOTHESIS: Eating disorders are over-represented in type 1 diabetes and are associated with an increased risk of complications, but it is unclear whether type 1 diabetes affects the treatment of eating disorders. We assessed incidence and treatment of eating disorders in a nationwide sample of individuals with type 1 diabetes and diabetes-free control individuals.

METHODS

Our study comprised 11,055 individuals aged <30 who had been diagnosed with type 1 diabetes in 1998-2010, and 11,055 diabetes-free control individuals matched for age, sex and hospital district. We ascertained incidence of eating disorders from hospital records using Poisson regression. Eating disorder treatment was assessed by new prescriptions for psychotropic medications and hospital treatment for eating disorders.

RESULTS

During a mean follow-up of 13.1 years, there were 175 incident cases of eating disorders among individuals with type 1 diabetes and 75 among the control individuals (adjusted incidence rate ratio 2.35; 95% CI 1.80, 3.09). The prescription of psychotropic medications was similar among eating disorder patients with and without type 1 diabetes. However, those with type 1 diabetes received outpatient hospital treatment for their eating disorder less often than those without diabetes (mean 3.32 vs 5.33 outpatient care visits per year [adjusted difference 1.24; 95% CI 0.39, 2.08]).

CONCLUSIONS/INTERPRETATION: People with type 1 diabetes are more likely to be diagnosed with eating disorders than their diabetes-free peers. However, they receive less outpatient hospital treatment for their eating disorders despite their greater risk for major adverse health outcomes. These findings emphasise the need for targeted eating disorder treatment for people with type 1 diabetes.

摘要

目的/假设:饮食失调在1型糖尿病患者中更为常见,且与并发症风险增加相关,但尚不清楚1型糖尿病是否会影响饮食失调的治疗。我们在全国范围内对1型糖尿病患者和无糖尿病对照个体进行了抽样,评估了饮食失调的发病率和治疗情况。

方法

我们的研究包括1998 - 2010年诊断为1型糖尿病的11055名30岁以下个体,以及11055名年龄、性别和医院辖区相匹配的无糖尿病对照个体。我们使用泊松回归从医院记录中确定饮食失调的发病率。通过精神药物新处方和饮食失调住院治疗来评估饮食失调的治疗情况。

结果

在平均13.1年的随访期间,1型糖尿病患者中有175例饮食失调新发病例,对照个体中有75例(调整后的发病率比为2.35;95%置信区间为1.80, 3.09)。有和没有1型糖尿病的饮食失调患者中精神药物的处方情况相似。然而,1型糖尿病患者因饮食失调接受门诊治疗的频率低于无糖尿病患者(每年平均门诊就诊次数分别为3.32次和5.33次[调整后的差异为1.24;95%置信区间为0.39, 2.08])。

结论/解读:1型糖尿病患者比无糖尿病的同龄人更易被诊断出饮食失调。然而,尽管他们面临更严重不良健康后果的风险更高,但因饮食失调接受的门诊治疗却更少。这些发现强调了针对1型糖尿病患者进行针对性饮食失调治疗的必要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c1ba/11950106/db3baf8ac36e/125_2024_6346_Fig1_HTML.jpg

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