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基于菱形概念的股骨和胫骨大尺寸缺损的手术不愈合治疗

Surgical nonunion treatment of large-sized defects of femur and tibia based on the diamond concept.

作者信息

Findeisen Sebastian, Mennerat Louis, Ferbert Thomas, Helbig Lars, Bewersdorf Tim N, Großner Tobias, Schamberger Christian, Schmidmaier Gerhard, Tanner Michael

机构信息

Clinic for Trauma and Reconstructive Surgery, Centre for Orthopedics, Trauma Surgery, and Paraplegiology, Heidelberg, Germany.

出版信息

Bone Jt Open. 2025 Jan 6;6(1):26-34. doi: 10.1302/2633-1462.61.BJO-2024-0096.R1.

Abstract

AIMS

The aim of this study was to evaluate the radiological outcome of patients with large bone defects in the femur and tibia who were treated according to the guidelines of the diamond concept in our department (Centre for Orthopedics, Trauma Surgery, and Paraplegiology).

METHODS

The following retrospective, descriptive analysis consists of patients treated in our department between January 2010 and December 2021. In total, 628 patients were registered, of whom 108 presented with a large-sized defect (≥ 5 cm). A total of 70 patients met the inclusion criteria. The primary endpoint was radiological consolidation of nonunions after one and two years via a modified Lane-Sandhu Score, including only radiological parameters.

RESULTS

The mean defect size was 6.77 cm (SD 1.86), with the largest defect being 12.6 cm. Within two years after surgical treatment, 45 patients (64.3%) presented consolidation of the previous nonunion. After one year, six patients (8.6%) showed complete consolidation and 23 patients (32.9%) showed a considerable callus formation, whereas 41 patients (58.6%) showed a Lane-Sandhu score of 2 or below. Two years after surgery, 24 patients (34.3%) were categorized as Lane-Sandhu score 4, another 23 patients (32.9%) reached a score of 3, while 14 patients (20.0%) remained without final consolidation (score ≤ 2). A total of nine patients (12.9%) missed the two-year follow-up. The mean follow-up was 44.40 months (SD 32.00). The mean time period from nonunion surgery to consolidation was 16.42 months (SD 9.73).

CONCLUSION

Patients with presentation of a large-sized nonunion require a structured and sufficiently long follow-up to secure the consolidation of the former nonunion. Furthermore, a follow-up of at least two years is required in order to declare a nonunion as consolidated, given that a significant part of the nonunions declared as not consolidated at one year showed consolidation within the second year. Moreover, the proven "gold standard" of a two-step procedure, so called Masquelet technique, shows effectiveness.

摘要

目的

本研究旨在评估股骨和胫骨大骨缺损患者按照我院(骨科、创伤外科和截瘫学中心)钻石概念指南进行治疗后的影像学结果。

方法

以下回顾性描述性分析纳入了2010年1月至2021年12月期间在我院接受治疗的患者。总共登记了628例患者,其中108例存在大尺寸缺损(≥5 cm)。共有70例患者符合纳入标准。主要终点是通过改良的Lane-Sandhu评分评估一年和两年后骨不连的影像学愈合情况,该评分仅包括影像学参数。

结果

平均缺损大小为6.77 cm(标准差1.86),最大缺损为12.6 cm。手术治疗后两年内,45例患者(64.3%)先前的骨不连实现了愈合。一年后,6例患者(8.6%)显示完全愈合,23例患者(32.9%)显示有大量骨痂形成,而41例患者(58.6%)的Lane-Sandhu评分为2分或更低。术后两年,24例患者(34.3%)被归类为Lane-Sandhu评分4分,另外23例患者(32.9%)评分为3分,而14例患者(20.0%)仍未实现最终愈合(评分≤2分)。共有9例患者(12.9%)未进行两年的随访。平均随访时间为44.40个月(标准差32.00)。从骨不连手术到愈合的平均时间为16.42个月(标准差9.73)。

结论

出现大尺寸骨不连的患者需要进行结构化且足够长的随访,以确保先前骨不连的愈合。此外,鉴于相当一部分在一年时被判定为未愈合的骨不连在第二年实现了愈合,因此需要至少两年的随访才能宣布骨不连已愈合。此外,已证实的两步法“金标准”,即所谓的Masquelet技术,显示出有效性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d54a/11700679/373262ba7b53/BJO-2024-0096.R1-galleyfig1.jpg

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