Barić Hrvoje, Komljenović Sara, Garcia Sergio Garcia, Niemelä Mika
Department of Neurosurgery, Helsinki University Hospital, Finland.
Zagreb University Medical School, Croatia.
Neurochirurgie. 2025 Mar;71(2):101632. doi: 10.1016/j.neuchi.2025.101632. Epub 2025 Jan 3.
Skull-base surgery, including skull-base meningiomas (SBMs), is among the most challenging medical fields which has witnessed leaps in advancement, owing to ever evolving technological and scientific progress. We performed a comprehensive bibliometric analysis and analysis of clinical reports on SBMs to describe the evolution and identify trends and relationships between basic and applied research in the field.
The study was a qualitative and quantitative bibliometric analysis of SBM research and review of SBM clinical series via a systematic search of the Web of Science for SBM topics and SBM case series. Quantitative analysis included the most cited publications, most productive authors, most cited journals, and number of publications per country. Keyword co-occurrence and co-authorship maps were produced to visualize research hotspots. Data output from the visualization analysis was analyzed qualitatively to identify themes within separate clusters and delineate evolution of clusters across time. Publications were screened to extract clinical reports of at least ten SBM cases to analyze year, type of treatment, country, and sample size in order to use the data to investigate the lag period between research and clinical adaptation of individual treatment modalities.
We identified 3258 publications and 451 series reporting on 33559 cases of SBMs. The United States of America is the leading country in publications and reported number of SBM cases. The most productive authors are active neurosurgeons in their 40s, or older. Among the top cited publications, most are related to endoscopic surgery, followed by research on genomics. Open surgery is the most common treatment modality being reported for SBM cases, however it's prevalence has been on the decrease as more recently there has been a substantial increase in other types of treatment.
Complexity of the field is reflected in the delayed age of peak scientific productivity. Over the past fifty years the SBM research has undergone a rapid expansion and can currently be seen as developing in four separate areas and the efforts are being led by three broadly collaborating research groups. The research-to-clinical routine lag of less than ten years speaks of the dynamic nature of SBM research and treatment.
颅底手术，包括颅底脑膜瘤（SBMs），是最具挑战性的医学领域之一，由于技术和科学的不断进步，该领域取得了飞跃式发展。我们对SBMs进行了全面的文献计量分析和临床报告分析，以描述该领域的发展演变，并确定基础研究与应用研究之间的趋势及关系。
本研究是对SBM研究的定性和定量文献计量分析，并通过系统检索科学网（Web of Science）中关于SBM主题和SBM病例系列的文献，对SBM临床系列进行综述。定量分析包括被引频次最高的出版物、产出最多的作者、被引频次最高的期刊以及每个国家的出版物数量。通过关键词共现和共同作者图谱来可视化研究热点。对可视化分析的数据输出进行定性分析，以识别不同聚类中的主题，并描绘各聚类随时间的演变。筛选出版物以提取至少10例SBM病例的临床报告，分析年份、治疗类型、国家和样本量，以便利用这些数据研究个体治疗方式在研究与临床应用之间的滞后时间。
我们识别出3258篇出版物和451个系列，报告了33559例SBM病例。美国是出版物数量和报告的SBM病例数最多的国家。产出最多的作者是40岁及以上活跃的神经外科医生。在被引频次最高的出版物中，大多数与内镜手术相关，其次是基因组学研究。开放手术是SBM病例报告中最常见的治疗方式，然而其患病率一直在下降，因为最近其他类型的治疗有了大幅增加。
该领域的复杂性体现在科学产出峰值年龄的延迟上。在过去五十年里，SBM研究经历了快速扩张，目前可视为在四个不同领域发展，且这些努力由三个广泛合作的研究团队引领。研究到临床常规应用的滞后时间不到十年，这表明SBM研究和治疗具有动态性。
