阿尔茨海默病患者小脑体积的放射解剖学评估
Radio-Anatomical Assessment of Cerebellum Volume in Individuals with Alzheimer's Disease.
作者信息
Acar Musa, Seker Busra, Ugur Sultan
机构信息
Department of Physiotherapy and Rehabilitation, Faculty of Nezahat Keleşoğlu Health Sciences, Necmettin Erbakan University, Konya, Turkey.
Department of Anatomy, Faculty of Medicine, Necmettin Erbakan University, Konya, Turkey.
出版信息
Curr Alzheimer Res. 2024;21(8):599-606. doi: 10.2174/0115672050365323241217175349.
INTRODUCTION
Alzheimer's disease is a chronic brain disease that includes memory and language disorders. This disease, which is considered the most common cause of dementia worldwide, accounts for 60-80% of all dementia cases. Recent studies suggest that the cerebellum may play a role in cognitive functions as well as motor functions.
MATERIALS AND METHODS
The study was conducted on 40 Alzheimer's patients and 40 healthy individuals. In our study, volumetric evaluation of the cerebellum was performed.
RESULTS
As expected, significant differences were found in cerebellar volume reduction in AD patients compared to healthy controls. Significant volume increase was observed in some regions of the cerebellum in Alzheimer's patients compared to healthy individuals.
CONCLUSION
The findings supported the role of the cerebellum in cognitive functions. Volume reductions may assist clinicians in making an early diagnosis of AD.
引言
阿尔茨海默病是一种慢性脑部疾病，包括记忆和语言障碍。这种疾病被认为是全球痴呆症最常见的病因，占所有痴呆症病例的60 - 80%。最近的研究表明，小脑可能在认知功能以及运动功能中发挥作用。
材料与方法
该研究对40名阿尔茨海默病患者和40名健康个体进行。在我们的研究中，对小脑进行了体积评估。
结果
正如预期的那样，与健康对照组相比，阿尔茨海默病患者的小脑体积减少存在显著差异。与健康个体相比，阿尔茨海默病患者小脑的某些区域观察到显著的体积增加。
结论
这些发现支持了小脑在认知功能中的作用。体积减少可能有助于临床医生对阿尔茨海默病进行早期诊断。
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