Schreuder Floris H B M, Gaberel Thomas, Cordonnier Charlotte
Department of Neurology, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, the Netherlands (F.H.B.M.S.).
Department of Neurosurgery, University Hospital of Caen, France (T.G.).
Stroke. 2025 Feb;56(2):575-578. doi: 10.1161/STROKEAHA.124.047467. Epub 2025 Jan 6.
After 30 years of disappointment, 2 randomized controlled trials investigating the effect of neurosurgical treatment on functional outcome in patients with intracerebral hemorrhage were published in 2024. The ENRICH trial (Early Minimally Invasive Removal of Intracerebral Hemorrhage) studied the efficacy of early minimally invasive hematoma removal in patients with lobar or anterior basal ganglia intracerebral hemorrhage, whereas the SWITCH trial investigated the effect of decompressive craniectomy without hematoma removal in severe deep intracerebral hemorrhage. In this critique article, we will discuss the main findings of these trials, their implications and future perspectives.