Khongyut Thanaphon, Panpikoon Tanapong, Buangam Chinnarat, Pichitpichatkul Kaewpitcha, Treesit Tharinton, Feinggumloon Sasikorn
Department of Diagnostic and Therapeutic Radiology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
Infect Prev Pract. 2024 Dec 5;7(1):100433. doi: 10.1016/j.infpip.2024.100433. eCollection 2025 Mar.
This study aimed to examine the correlation between subcutaneous fat thickness and chemoport-related infection and to determine the risk factors that lead to complications associated with chemoport.
This study retrospectively reviewed 363 patients with chemoport insertion between May 2018 and May 2022. The patients were classified into three groups, with 121 patients in each group, based on the tertiles of subcutaneous fat thickness measured in the computed tomography (CT) scan. The incidence of short-term and long-term complications, including dislocation, infection, and malfunction, were obtained and compared between the three groups. The risk factors of chemoport-related complications were analysed in multivariate analysis.
The incidence of infection in the low, middle, and high subcutaneous fat thickness groups were 1.7%, 3.3%, and 0%, respectively ( = 0.131). No short-term complications occurred in this study group. After one year of follow-up, 11 patients (3.0%) had long-term complications; 6 patients (1.7%) developed chemoport infection, while five patients (1.4%) had chemoport dislocation. In multivariate analysis, the risk of dislocation was significantly higher when insertion was performed via the left internal jugular vein (OR = 9.87, =0.033).
The thickness of subcutaneous fat does not significantly correlate with the incidence of chemoport infection, and placement of the port on the left side of the chest wall via the left internal jugular vein is the risk factor for chemoport dislocation.
本研究旨在探讨皮下脂肪厚度与化疗端口相关感染之间的相关性，并确定导致化疗端口相关并发症的危险因素。
本研究回顾性分析了2018年5月至2022年5月期间363例行化疗端口置入术的患者。根据计算机断层扫描（CT）测量的皮下脂肪厚度三分位数，将患者分为三组，每组121例。获取并比较三组患者短期和长期并发症（包括移位、感染和功能障碍）的发生率。多因素分析化疗端口相关并发症的危险因素。
皮下脂肪厚度低、中、高组的感染发生率分别为1.7%、3.3%和0%（P=0.131）。本研究组未发生短期并发症。随访一年后，11例患者（3.0%）出现长期并发症；6例患者（1.7%）发生化疗端口感染，5例患者（1.4%）出现化疗端口移位。多因素分析显示，经左颈内静脉置入时移位风险显著更高（OR=9.87，P=0.033）。
皮下脂肪厚度与化疗端口感染发生率无显著相关性，经左颈内静脉在胸壁左侧放置端口是化疗端口移位的危险因素。
