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急性横贯性脊髓炎作为神经型布鲁氏菌病的罕见表现:一例报告

Acute Transverse Myelitis as an Uncommon Presentation of Neurobrucellosis: A Case Report.

作者信息

Karaja Saja, Kazkz Waddah

机构信息

Faculty of Medicine Hama University Hama Syria.

出版信息

Clin Case Rep. 2025 Jan 2;13(1):e70060. doi: 10.1002/ccr3.70060. eCollection 2025 Jan.

DOI:10.1002/ccr3.70060
PMID:39759187
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11695208/
Abstract

Brucellosis mainly affects the musculoskeletal system with neurological manifestations observed in < 5% of all cases. This report outlines a unique case of neurobrucellosis that resulted in acute transverse myelitis (TM) with absent deep reflexes and negative Wright's reaction. In endemic regions, neurobrocellosis should be considered as a potential etiology of acute TM. Timely initiation of treatment is essential for optimizing clinical outcomes.

摘要

布鲁氏菌病主要影响肌肉骨骼系统,在所有病例中,神经表现的发生率低于5%。本报告概述了一例独特的神经型布鲁氏菌病病例,该病例导致急性横贯性脊髓炎(TM),伴有深反射消失和莱特反应阴性。在流行地区,神经型布鲁氏菌病应被视为急性TM的潜在病因。及时开始治疗对于优化临床结果至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac68/11695208/ef681f162991/CCR3-13-e70060-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac68/11695208/ef681f162991/CCR3-13-e70060-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac68/11695208/ef681f162991/CCR3-13-e70060-g001.jpg

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本文引用的文献

1
Transverse myelitis in children and adults.儿童和成人的横贯性脊髓炎。
Handb Clin Neurol. 2023;196:101-117. doi: 10.1016/B978-0-323-98817-9.00020-X.
2
Human brucellosis and fever of unknown origin.人布鲁氏菌病与不明原因发热。
BMC Infect Dis. 2022 Nov 21;22(1):868. doi: 10.1186/s12879-022-07872-8.
3
Neurobrucellosis: report of 54 cases.神经型布鲁氏菌病:54例报告
Trop Med Health. 2022 Oct 14;50(1):77. doi: 10.1186/s41182-022-00472-x.
4
Manifestations, complications, and treatment of neurobrucellosis: a systematic review and meta-analysis.神经布鲁菌病的表现、并发症和治疗:系统评价和荟萃分析。
Int J Neurosci. 2024 Jun;134(3):256-266. doi: 10.1080/00207454.2022.2100776. Epub 2022 Aug 5.
5
Subacute transverse myelitis as a clinical presentation of neurobrucellosis.亚急性横贯性脊髓炎作为神经型布鲁氏菌病的一种临床表现。
J Infect Dev Ctries. 2021 Sep 30;15(9):1359-1363. doi: 10.3855/jidc.14753.
6
Recurrent Encephalopathy with Transverse Myelitis: An Uncommon Presentation of Neurobrucellosis.复发性脑病合并横贯性脊髓炎:神经型布鲁氏菌病的罕见表现
J Neurosci Rural Pract. 2019 Oct;10(4):703-706. doi: 10.1055/s-0039-1700600. Epub 2019 Dec 11.
7
Laboratory Diagnosis of Human Brucellosis.人布鲁氏菌病的实验室诊断。
Clin Microbiol Rev. 2019 Nov 13;33(1). doi: 10.1128/CMR.00073-19. Print 2019 Dec 18.
8
Myelitis and Polyradiculoneuropathy With Severe Pain: Unusual Neurological Manifestations as Presenting Symptoms of Brucellosis.伴有严重疼痛的脊髓炎和多发性神经根神经病:作为布鲁氏菌病首发症状的不寻常神经表现
Neurologist. 2018 Jul;23(4):131-134. doi: 10.1097/NRL.0000000000000184.
9
Transverse myelitis--a review of the presentation, diagnosis, and initial management.横贯性脊髓炎——临床表现、诊断及初始治疗综述
Discov Med. 2013 Oct;16(88):167-77.
10
Central nervous system brucellosis: presentation, diagnosis and treatment.中枢神经系统布鲁氏菌病:临床表现、诊断与治疗
J Infect. 1998 May;36(3):297-301. doi: 10.1016/s0163-4453(98)94279-7.