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[髓外造血组织所致截瘫的放射治疗]

[Radiotherapy of paraplegia caused by extramedullary hematopoietic tissue].

作者信息

Dietz R, Niewald M, Schnabel K, Berberich W

出版信息

Strahlentherapie. 1985 Mar;161(3):140-2.

PMID:3975948
Abstract

The presentation by computed tomography of an extramedullar epidural intraspinal hemopoisis has only been described sporadically. It has been possible to visualize by CT-scans the regression under radiotherapy of a sensory and motor paraplegia in a 17 years old patient with beta-thalassemia major. The central nervous system (thoracic and lumbar zone as well as os sacrum) was exposed to a total reference dose of 30 Gy which was administered within twenty days by a 60Co unit in single doses of 2 Gy each. From 4 Gy on, the paraplegic symptoms regressed continuously. The control CT taken after 26 Gy- the paraplegia had completely disappeared at this time-showed a significant regression of the intraspinal soft tissue masses. Radiotherapy is very important in the treatment of this disease. A direct correlation is found between clinical symptoms and CT-presentation.

摘要

髓外硬膜内脊髓造血的计算机断层扫描表现仅偶尔有描述。通过CT扫描已能够观察到一名17岁重型β地中海贫血患者在放疗后感觉和运动性截瘫的消退情况。中枢神经系统(胸段和腰段以及骶骨)接受了30 Gy的总参考剂量,由60Co单位在20天内分单次剂量2 Gy给予。从4 Gy开始,截瘫症状持续消退。在26 Gy后进行的对照CT(此时截瘫已完全消失)显示脊髓内软组织肿块明显消退。放疗在这种疾病的治疗中非常重要。临床症状与CT表现之间存在直接关联。

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