一项比较年度与两年一次乳房X光检查之间乳腺癌检出率的回顾性图表分析。

A Retrospective Chart Analysis Comparing Breast Cancer Detection Rates Between Annual Versus Biennial Mammograms.

作者信息

Patel Pavan, Sakhi Hifza, Kalvapudi Devaki, Changas Angelo, Sulaimanov Mukhamed, Gutierrez Brian Criollo, Umana Idopise, Slaton Jake A, Singh Hardeep

机构信息

Transitional Year, Northeast Georgia Medical Center, Gainesville, GA, USA.

GME Research, Northeast Georgia Medical Center, Gainesville, GA, USA.

出版信息

J Clin Med Res. 2024 Dec;16(12):608-624. doi: 10.14740/jocmr6081. Epub 2024 Dec 20.

DOI:10.14740/jocmr6081

PMID:39759488

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11699865/

Abstract

BACKGROUND

Per American Cancer Society, breast cancer is one of the most prevalent causes of cancer-related mortality in women in the United States. Different organizations vary in their recommendations regarding frequency of mammograms, with the United State Preventive Service Taskforce recommending biennial screening and other organizations like American College of Radiology promoting annual screening. The purpose of this study was to analyze institutional data to compare breast cancer detection rates among women undergoing annual vs. biennial mammograms.

METHODS

In this retrospective chart review, we analyzed deidentified records of women aged 25 to 74 at Northeast Georgia Health System, who had undergone at least two screening mammograms and were diagnosed with primary breast cancer. We analyzed several variables including Breast Imaging Reporting and Data System (BI-RADS) categorization, estrogen receptor (ER) status, progesterone receptor (PR) status, human epidermal growth factor receptor 2 (HER2) status, age, race, ethnicity, nodal involvement, smoking status, insurance status, grade, tumor size, number of screening mammograms, personal history of breast cancer, family history of breast cancer, and their correlation to screening frequency (annual vs. biennial vs. less than biennial).

RESULTS

Among the total 2,219 records that satisfied the inclusion criteria, we observed that BI-RADS categorization (P < 0.001), ER status (P = 0.003), and PR status (P = 0.001) were associated with mammogram screening frequency while the other variables were not statistically significant. analysis revealed that biennially screened patients exhibited less N2 node involvement than expected (P = 0.022). Additionally, Hispanic/Latino(a) patients had a greater frequency of biennial screenings than expected (P = 0.050). Lastly, analysis revealed that current smokers had a greater incidence of less-frequent-than-biennial screenings (P = 0.023).

CONCLUSIONS

Annual mammograms were associated with a lower BI-RADS stage and lower stage of breast cancer diagnosis.

摘要

背景

根据美国癌症协会的数据，乳腺癌是美国女性癌症相关死亡的最常见原因之一。不同组织对于乳房X光检查的频率建议各不相同，美国预防服务工作组建议每两年进行一次筛查，而美国放射学会等其他组织则提倡每年进行筛查。本研究的目的是分析机构数据，以比较每年接受一次与每两年接受一次乳房X光检查的女性的乳腺癌检出率。

方法

在这项回顾性病历审查中，我们分析了佐治亚州东北部医疗系统中年龄在25至74岁之间、至少接受过两次乳房X光筛查且被诊断为原发性乳腺癌的女性的匿名记录。我们分析了多个变量，包括乳房影像报告和数据系统（BI-RADS）分类、雌激素受体（ER）状态、孕激素受体（PR）状态、人表皮生长因子受体2（HER2）状态、年龄、种族、民族、淋巴结受累情况、吸烟状况、保险状况、分级、肿瘤大小、乳房X光筛查次数、个人乳腺癌病史、乳腺癌家族史，以及它们与筛查频率（每年一次、每两年一次、少于每两年一次）的相关性。

结果

在总共2219份符合纳入标准的记录中，我们观察到BI-RADS分类（P < 0.001）、ER状态（P = 0.003）和PR状态（P = 0.001）与乳房X光筛查频率相关，而其他变量无统计学意义。分析显示，每两年接受筛查的患者N2淋巴结受累情况低于预期（P = 0.022）。此外，西班牙裔/拉丁裔患者每两年接受筛查的频率高于预期（P = 0.050）。最后，分析显示，目前吸烟者接受少于每两年一次筛查的发生率更高（P = 0.023）。