Girnyi Sergii, Marano Luigi, Skokowski Jaroslaw, Mocarski Piotr, Kycler Witold, Gallo Gaetano, Dyzmann-Sroka Agnieszka, Kazmierczak-Siedlecka Karolina, Kalinowski Leszek, Banasiewicz Tomasz, Polom Karol
Department of General Surgery and Surgical Oncology, "Saint Wojciech" Hospital, "Nicolaus Copernicus" Health Center, Gdansk, Poland.
Department of Medicine, Academy of Applied Medical and Social Sciences (AMiSNS), Elblag, Poland.
Rep Pract Oncol Radiother. 2024 Dec 4;29(5):614-626. doi: 10.5603/rpor.103136. eCollection 2024.
Gastrointestinal (GI) cancer patients undergoing surgery are particularly vulnerable to malnutrition, which can significantly impact surgical outcomes. Prehabilitation interventions encompassing nutritional, physical, and psychosocial support have gained attention for their potential to mitigate these risks. However, the efficacy of multidisciplinary prehabilitation programs in this context remains underexplored. This narrative review synthesizes existing literature to evaluate the effectiveness of prehabilitation interventions in improving outcomes for GI cancer patients undergoing surgery. Drawing on a comprehensive analysis of available evidence, the review examines the integration of nutritional, physical, and psychosocial interventions and explores the implications for clinical practice and future research. The review highlights the importance of standardized protocols and interdisciplinary collaboration in optimizing prehabilitation programs for GI cancer patients. It identifies gaps in current research, particularly regarding the synergistic effects of integrating various intervention modalities and the role of innovative strategies such as immunonutrition. Moreover, the review underscores the need for larger studies to assess the effectiveness of multimodal prehabilitation approaches and establish standardized outcome measures. In conclusion, despite advancements in understanding the importance of prehabilitation, significant gaps persist in the literature, warranting further research to refine prehabilitation protocols and improve perioperative outcomes for GI cancer patients. By addressing these research gaps and fostering interdisciplinary partnerships, future studies have the potential to enhance the effectiveness of prehabilitation interventions and optimize perioperative care in this population.
接受手术的胃肠道（GI）癌症患者特别容易出现营养不良，这会对手术结果产生重大影响。包括营养、身体和心理社会支持的术前康复干预因其减轻这些风险的潜力而受到关注。然而，多学科术前康复计划在这种情况下的疗效仍未得到充分探索。这篇叙述性综述综合了现有文献，以评估术前康复干预对改善接受手术的GI癌症患者预后的有效性。通过对现有证据的全面分析，该综述考察了营养、身体和心理社会干预的整合情况，并探讨了其对临床实践和未来研究的意义。该综述强调了标准化方案和跨学科合作在优化GI癌症患者术前康复计划中的重要性。它指出了当前研究中的空白，特别是关于整合各种干预方式的协同效应以及免疫营养等创新策略的作用。此外，该综述强调需要进行更大规模的研究，以评估多模式术前康复方法的有效性并建立标准化的结局指标。总之，尽管在理解术前康复的重要性方面取得了进展，但文献中仍存在重大空白，需要进一步研究以完善术前康复方案并改善GI癌症患者的围手术期结局。通过解决这些研究空白并促进跨学科合作，未来的研究有可能提高术前康复干预的有效性，并优化该人群的围手术期护理。
