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罕见肾恶性肿瘤:病例系列研究凸显罕见表现及其管理策略

Rare Renal Malignancies: A Case Series Highlighting Uncommon Presentations and Their Management Strategies.

作者信息

Haritha Annem, A Sri Balram, Murthy N Rama

机构信息

College of Medicine, Mamata Academy of Medical Sciences, Bachupally, IND.

Department of Urology, Mamata Academy of Medical Sciences, Bachupally, IND.

出版信息

Cureus. 2024 Dec 4;16(12):e75119. doi: 10.7759/cureus.75119. eCollection 2024 Dec.

DOI:10.7759/cureus.75119
PMID:39759602
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11698686/
Abstract

This case series elucidates renal cell carcinoma characterized by three distinct presentations, necessitating individualized treatment strategies tailored to each specific circumstance. The three cases presented pertain to clear cell renal cell carcinoma. The first case involves a 44-year-old male patient with renal cell carcinoma in an ectopic kidney, an exceedingly rare occurrence with limited literature. An open transperitoneal radical nephrectomy was undertaken. The second case pertains to a 33-year-old male patient with renal cell carcinoma situated in the lower pole of the left kidney for which partial nephrectomy was planned and performed. The third case concerns a 57-year-old male patient with renal cell carcinoma found in the right lower pole of the kidney, involving invasion into the inferior vena cava (IVC). A radical nephrectomy with tumor thrombectomy was meticulously planned and successfully performed.

摘要

本病例系列阐明了具有三种不同表现形式的肾细胞癌,这需要针对每种具体情况制定个性化的治疗策略。所呈现的三个病例均为透明细胞肾细胞癌。首例病例为一名44岁男性患者,其异位肾患有肾细胞癌,这种情况极为罕见,相关文献有限。实施了开放性经腹根治性肾切除术。第二例病例是一名33岁男性患者,其左肾下极患有肾细胞癌,为此计划并实施了部分肾切除术。第三例病例涉及一名57岁男性患者,其右肾下极发现肾细胞癌,且已侵犯下腔静脉(IVC)。精心计划并成功实施了根治性肾切除术及肿瘤血栓切除术。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/94e2/11698686/18da2a191bab/cureus-0016-00000075119-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/94e2/11698686/41c48f1f6b1b/cureus-0016-00000075119-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/94e2/11698686/0327a779c989/cureus-0016-00000075119-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/94e2/11698686/fc7300be03a6/cureus-0016-00000075119-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/94e2/11698686/2ecad50a5ec9/cureus-0016-00000075119-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/94e2/11698686/18da2a191bab/cureus-0016-00000075119-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/94e2/11698686/41c48f1f6b1b/cureus-0016-00000075119-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/94e2/11698686/0327a779c989/cureus-0016-00000075119-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/94e2/11698686/fc7300be03a6/cureus-0016-00000075119-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/94e2/11698686/2ecad50a5ec9/cureus-0016-00000075119-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/94e2/11698686/18da2a191bab/cureus-0016-00000075119-i05.jpg

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本文引用的文献

1
Surgical Trends and Complications in Partial and Radical Nephrectomy: Results from the GRAND Study.部分肾切除术和根治性肾切除术的手术趋势及并发症:GRAND研究结果
Cancers (Basel). 2023 Dec 24;16(1):97. doi: 10.3390/cancers16010097.
2
Clear cell renal cell carcinoma ontogeny and mechanisms of lethality.透明细胞肾细胞癌的发生机制及致死机制。
Nat Rev Nephrol. 2021 Apr;17(4):245-261. doi: 10.1038/s41581-020-00359-2. Epub 2020 Nov 3.
3
Partial Versus Radical Nephrectomy in Patients with Renal Cell Carcinoma: A Systematic Review and Meta-analysis.
肾细胞癌患者的部分肾切除术与根治性肾切除术:一项系统评价和荟萃分析
Urol J. 2020 Mar 16;17(2):109-117. doi: 10.22037/uj.v0i0.5358.
4
Renal cell carcinoma: a review of biology and pathophysiology.肾细胞癌:生物学与病理生理学综述
F1000Res. 2018 Mar 12;7:307. doi: 10.12688/f1000research.13179.1. eCollection 2018.
5
Partial Nephrectomy Versus Radical Nephrectomy for Clinical T1b and T2 Renal Tumors: A Systematic Review and Meta-analysis of Comparative Studies.部分肾切除术与根治性肾切除术治疗 T1b 和 T2 期临床肾肿瘤的比较:系统评价和荟萃分析。
Eur Urol. 2017 Apr;71(4):606-617. doi: 10.1016/j.eururo.2016.08.060. Epub 2016 Sep 7.