Hazim Asmaa, Mimouni Yasmine, Saaf Sarra, Sodki Mustapha, Beniaz Fatema Zahra
Neurology, Cheikh Khalifa International University Hospital, Mohammed VI International University Hospital, Casablanca, MAR.
Neurology, Hôpital Cheikh Khalifa Bin Zayed, Casablanca, MAR.
Cureus. 2024 Dec 6;16(12):e75227. doi: 10.7759/cureus.75227. eCollection 2024 Dec.
We report the case of a 22-year-old mother with no medical history, admitted for gram-negative meningitis, identified as , 15 days after spinal anaesthesia. She was initially treated with dual antibiotic therapy, consisting of ceftazidime (2g three times a day) and amikacin. The first lumbar puncture (LP) performed 10 days approximately after the beginning of the treatment found no bacterial growth on the CSF culture. However, after 21 days of well-conducted treatment, she relapsed, and the was once again detected on the CSF culture. The therapeutic protocol was changed, and she began meropenem and ciprofloxacin, which was pursued for six weeks. She improved clinically and biologically and was discharged after nearly 90 days of hospitalisation.
我们报告了一例22岁无病史的母亲，因革兰氏阴性脑膜炎入院，该病例在脊髓麻醉15天后确诊。她最初接受了由头孢他啶（每日3次，每次2g）和阿米卡星组成的双联抗生素治疗。在治疗开始约10天后进行的首次腰椎穿刺（LP）脑脊液培养未发现细菌生长。然而，在进行了21天规范治疗后，她复发了，脑脊液培养再次检测到[未提及的细菌名称]。治疗方案改变，她开始使用美罗培南和环丙沙星，持续了六周。她在临床和生物学方面均有改善，住院近90天后出院。
