Labib Islam, Weitz Jürgen, Hempel Sebastian
Klinik und Poliklinik für Viszeral‑, Thorax- und Gefäßchirurgie, Universitätsklinikum und Medizinische Fakultät Carl Gustav Carus, Technische Universität Dresden, Fetscherstraße 74, 01307, Dresden, Deutschland.
Chirurgie (Heidelb). 2025 Feb;96(2):108-112. doi: 10.1007/s00104-024-02223-6. Epub 2025 Jan 6.
Pancreatic surgery is still associated with significant morbidity. In a simultaneously increasingly ageing population with elevated morbidity, the risk stratification and indications for surgery are of particular importance.
Assessment of the impact of multimorbidity of patients on the postoperative outcome after pancreatic surgery.
Evaluation and summary of the available literature.
The postoperative morbidity after pancreatic surgery remains high. Relevant comorbidities, such as liver cirrhosis, cardiac and pulmonary diseases and advanced renal insufficiency enormously increase the risk of perioperative morbidity and mortality; however, in high-volume centers with appropriate expertise in pancreatic surgery the mortality is below 5%.
Pancreatic surgery with severe comorbidity can be safely performed in centers with proven expertise. Nevertheless, a careful interpretation of the indications and good patient selection are essential for the postoperative outcome.
胰腺手术仍伴有较高的发病率。在人口老龄化日益加剧且发病率不断上升的情况下，手术风险分层及手术指征尤为重要。
评估患者多种疾病并存对胰腺手术后预后的影响。
对现有文献进行评估与总结。
胰腺手术后的发病率仍然很高。诸如肝硬化、心肺疾病及晚期肾功能不全等相关合并症会极大增加围手术期发病及死亡风险；然而，在具备胰腺手术专业技能的大型中心，死亡率低于5%。
在具备可靠专业技能的中心，严重合并症患者也可安全地接受胰腺手术。尽管如此，谨慎解读手术指征及做好患者选择对术后预后至关重要。
