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Postoperative Adjuvant Dupilumab Improved Immediate Recovery in Patients With Advanced Type 2 Chronic Rhinosinusitis: An Exploratory Pilot Study.

作者信息

Ho Yan-Ting, Wang Hsiang-Sheng, Lee Ta-Jen, Chang Po-Hung, Wu Chia-Chen, Fu Chia-Hsiang

机构信息

Department of Otolaryngology, Head and Neck Surgery, Chang Gung Memorial Hospital and Chang Gung University, Taoyuan, Taiwan.

Department of Pathology, Linkou Chang Gung Memorial Hospital, Taoyuan City, Taiwan.

出版信息

Int Forum Allergy Rhinol. 2025 Apr;15(4):455-459. doi: 10.1002/alr.23523. Epub 2025 Jan 6.

DOI:10.1002/alr.23523
PMID:39761368
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11970449/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fadf/11970449/c6db721e65a4/ALR-15-455-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fadf/11970449/c6db721e65a4/ALR-15-455-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fadf/11970449/c6db721e65a4/ALR-15-455-g001.jpg

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Postoperative Adjuvant Dupilumab Improved Immediate Recovery in Patients With Advanced Type 2 Chronic Rhinosinusitis: An Exploratory Pilot Study.术后辅助使用度普利尤单抗可改善晚期2型慢性鼻-鼻窦炎患者的即刻恢复:一项探索性初步研究。
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Real life data with a six months follow-up from dietary interventions, biologic therapy and functional endoscopic surgery (FESS) in patients with chronic rhinosinusitis with nasal polyps (CRSwNP).对伴有鼻息肉的慢性鼻-鼻窦炎(CRSwNP)患者进行饮食干预、生物治疗和功能性鼻内镜手术(FESS)并随访6个月的真实生活数据。
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Int Forum Allergy Rhinol. 2022 Aug;12(8):986-995. doi: 10.1002/alr.22951. Epub 2022 Jan 10.
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Real-world effectiveness of dupilumab in a European cohort of chronic rhinosinusitis with nasal polyps (CHRINOSOR).度普利尤单抗在欧洲慢性鼻-鼻窦炎伴鼻息肉队列(CHRINOSOR)中的真实世界疗效
J Allergy Clin Immunol. 2025 Feb;155(2):451-460. doi: 10.1016/j.jaci.2024.10.016. Epub 2024 Oct 31.
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Real-world predictors of dupilumab prescription in patients with chronic rhinosinusitis with nasal polyps.慢性鼻-鼻窦炎伴鼻息肉患者中度普利尤单抗处方的真实世界预测因素
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本文引用的文献

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Rate of dupilumab use and symptom severity of patients with chronic rhinosinusitis with nasal polyposis after Draf 3 frontal sinusotomy.Draf 3额窦切开术后慢性鼻-鼻窦炎伴鼻息肉患者的度普利尤单抗使用率及症状严重程度
Int Forum Allergy Rhinol. 2024 Dec;14(12):1849-1856. doi: 10.1002/alr.23424. Epub 2024 Aug 7.
2
Role of serum eosinophil cationic protein in distinct endotypes of chronic rhinosinusitis.血清嗜酸性粒细胞阳离子蛋白在慢性鼻-鼻窦炎不同表型中的作用。
Rhinology. 2024 Feb 1;62(1):111-118. doi: 10.4193/Rhin23.170.
3
Predictors of persistent disease in biologic treated type 2 diffuse/eosinophilic chronic rhinosinusitis undergoing surgery.
生物治疗的 2 型弥漫性/嗜酸性慢性鼻鼻窦炎患者行手术治疗后持续性疾病的预测因素。
Int Forum Allergy Rhinol. 2024 May;14(5):909-918. doi: 10.1002/alr.23282. Epub 2023 Oct 8.
4
Blood eosinophils to direct oral corticosteroid treatment for patients with nasal polyps â€" an open label, non-inferiority, randomized control trial.血液嗜酸性粒细胞指导鼻息肉患者口服皮质类固醇治疗:一项开放标签、非劣效性、随机对照试验。
Rhinology. 2023 Aug 1;61(4):328-337. doi: 10.4193/Rhin22.328.
5
Olfaction Now and in the Future in CRSwNP.慢性鼻-鼻窦炎伴鼻息肉(CRSwNP)当下及未来的嗅觉研究
Am J Rhinol Allergy. 2023 Mar;37(2):168-174. doi: 10.1177/19458924231153485.
6
A comparative analysis of endoscopic sinus surgery versus biologics for treatment of chronic rhinosinusitis with nasal polyposis.内镜鼻窦手术与生物制剂治疗伴有鼻息肉的慢性鼻-鼻窦炎的对比分析。
Int Forum Allergy Rhinol. 2023 Feb;13(2):116-128. doi: 10.1002/alr.23059. Epub 2022 Sep 4.
7
Clinical characteristics of central compartment atopic disease in Southern China.中国南方中央隔室特应性疾病的临床特征。
Int Forum Allergy Rhinol. 2023 Mar;13(3):205-215. doi: 10.1002/alr.23069. Epub 2022 Sep 21.
8
Economic Evaluation of Dupilumab Versus Endoscopic Sinus Surgery for the Treatment of Chronic Rhinosinusitis With Nasal Polyps.度普利尤单抗与鼻内镜手术治疗鼻息肉慢性鼻窦炎的经济学评价
Int Forum Allergy Rhinol. 2022 Jun;12(6):813-820. doi: 10.1002/alr.22936. Epub 2022 Jan 5.
9
European Position Paper on Rhinosinusitis and Nasal Polyps 2020.欧洲鼻窦炎和鼻息肉 2020 年立场文件。
Rhinology. 2020 Feb 20;58(Suppl S29):1-464. doi: 10.4193/Rhin20.600.
10
Revision surgery rates in chronic rhinosinusitis with nasal polyps: meta-analysis of risk factors.慢性鼻-鼻窦炎伴鼻息肉患者的翻修手术率:危险因素的荟萃分析。
Int Forum Allergy Rhinol. 2020 Feb;10(2):199-207. doi: 10.1002/alr.22487. Epub 2019 Nov 21.