Pham Huyen, Bui Thanh C, Glass Joseph E, Back Sudie E, Le Phuc
Department of Psychiatry and Biobehavioral Sciences, University of California Los Angeles, 760 Westwood Plaza, Los Angeles, CA 90095, USA.
TSET Health Promotion Research Center, Stephenson Cancer Center, University of Oklahoma Health Sciences Center, 800 NE 10th St #3101, Oklahoma City, OK 73104, USA.
Alcohol Alcohol. 2024 Nov 18;60(1). doi: 10.1093/alcalc/agae091.
People often drink alcohol and use other substances concurrently, increasing the risk of adverse health outcomes. Our aims were to: (i) assess temporal trends in tobacco and/or cannabis use by varying alcohol consumption levels and (ii) identify associated factors of polysubstance use in high-risk alcohol users.
We conducted a repeated cross-sectional study combining 2010-19 U.S. National Survey of Drug Use and Health (NSDUH). Alcohol consumption was categorized as no use, low-risk use, and high-risk use. Outcomes include past-month tobacco and/or cannabis use, nicotine dependence, and/or frequent cannabis use. We employed linear time trends and multivariable logistic regressions.
We included 395 256 participants aged ≥18 years. From 2010 to 2019, the prevalence of tobacco use and nicotine dependence decreased while that of any and frequent cannabis use increased (P < .05). Tobacco use decreased faster in people with low-/high-risk alcohol use than no use (24% and 22% vs. 16%), whereas any cannabis use increased more rapidly in the no use group (155% vs. 77% in low- and 31% increase in high-risk groups). Among those with high-risk alcohol use, Hispanic individuals were less likely to use tobacco, cannabis, and both tobacco and cannabis, while non-Hispanic Black (NH Black) were more likely to use cannabis and both tobacco and cannabis than NH White counterparts (P < .05).
Past-month tobacco use decreased, while cannabis use increased significantly across all alcohol consumption levels. Sociodemographic subgroups, such as NH Black individuals and those with psychiatric comorbidities, showed increased odds of polysubstance use, underscoring the need for targeted public health interventions.
人们经常同时饮酒和使用其他物质，这增加了不良健康后果的风险。我们的目的是：（i）通过不同的酒精消费水平评估烟草和/或大麻使用的时间趋势，以及（ii）确定高风险酒精使用者中多物质使用的相关因素。
我们进行了一项重复横断面研究，结合了2010 - 2019年美国国家药物使用和健康调查（NSDUH）。酒精消费被分类为不使用、低风险使用和高风险使用。结果包括过去一个月的烟草和/或大麻使用、尼古丁依赖和/或频繁使用大麻。我们采用了线性时间趋势和多变量逻辑回归。
我们纳入了395256名年龄≥18岁的参与者。从2010年到2019年，烟草使用和尼古丁依赖的患病率下降，而任何大麻使用和频繁使用大麻的患病率上升（P < 0.05）。低/高风险酒精使用者中烟草使用的下降速度比不使用者更快（分别为24%和22%，而不使用者为16%），而不使用组中任何大麻使用的增加速度更快（155%，低风险组为77%，高风险组增加31%）。在高风险酒精使用者中，西班牙裔个体使用烟草、大麻以及同时使用烟草和大麻的可能性较小，而非西班牙裔黑人（NH黑人）比NH白人更有可能使用大麻以及同时使用烟草和大麻（P < 0.05）。
过去一个月的烟草使用下降，而在所有酒精消费水平上大麻使用显著增加。社会人口亚组，如NH黑人个体和患有精神疾病合并症的个体，多物质使用的几率增加，这突出了针对性公共卫生干预措施的必要性。
