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Unlocking new potential: the evolving landscape of metformin repurposing trials.

作者信息

Zhou Yating, Xue Fei

机构信息

Kunshan Hospital of Traditional Chinese Medicine, 388 Zuchongzhi South Road,Kunshan City, Suzhou, Jiangsu, China.

出版信息

J Transl Med. 2025 Jan 7;23(1):24. doi: 10.1186/s12967-024-06061-2.

DOI:10.1186/s12967-024-06061-2

PMID:39762963

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11705893/

Abstract

摘要

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本文引用的文献

Emerging role of Metformin in Alzheimer's disease: A translational view.

Ageing Res Rev. 2024 Sep;100:102439. doi: 10.1016/j.arr.2024.102439. Epub 2024 Jul 27.

Metformin as anticancer agent and adjuvant in cancer combination therapy: Current progress and future prospect.

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Metformin: update on mechanisms of action and repurposing potential.

Nat Rev Endocrinol. 2023 Aug;19(8):460-476. doi: 10.1038/s41574-023-00833-4. Epub 2023 May 2.

Harnessing the soil: reshaping the tumor microenvironment towards an antitumor immune state by low-dose metformin.

Cancer Commun (Lond). 2021 Aug;41(8):637-641. doi: 10.1002/cac2.12196. Epub 2021 Jul 20.

The effects of metformin on autophagy.

Biomed Pharmacother. 2021 May;137:111286. doi: 10.1016/j.biopha.2021.111286. Epub 2021 Jan 30.

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本文引用的文献

Emerging role of Metformin in Alzheimer's disease: A translational view.

Ageing Res Rev. 2024 Sep;100:102439. doi: 10.1016/j.arr.2024.102439. Epub 2024 Jul 27.

Metformin as anticancer agent and adjuvant in cancer combination therapy: Current progress and future prospect.

Transl Oncol. 2024 Jun;44:101945. doi: 10.1016/j.tranon.2024.101945. Epub 2024 Mar 30.

Metformin: update on mechanisms of action and repurposing potential.

Nat Rev Endocrinol. 2023 Aug;19(8):460-476. doi: 10.1038/s41574-023-00833-4. Epub 2023 May 2.

Harnessing the soil: reshaping the tumor microenvironment towards an antitumor immune state by low-dose metformin.

Cancer Commun (Lond). 2021 Aug;41(8):637-641. doi: 10.1002/cac2.12196. Epub 2021 Jul 20.

The effects of metformin on autophagy.

Biomed Pharmacother. 2021 May;137:111286. doi: 10.1016/j.biopha.2021.111286. Epub 2021 Jan 30.