Helmark Charlotte, Ahm Robert, Brandes Axel, Skovbakke Søren J, Nielsen Jens Cosedis, Frostholm Lisbeth, Taylor Rod S, Pedersen Susanne S
Department of Cardiology, Zealand University Hospital, Roskilde, Denmark.
Department of Psychology, University of Southern Denmark, Odense, Denmark.
Pilot Feasibility Stud. 2025 Jan 6;11(1):2. doi: 10.1186/s40814-024-01586-1.
Approximately 30% of patients with atrial fibrillation suffer from depression. Depression in patients with atrial fibrillation is associated with poor health outcomes, reduced health-related quality of life, and elevated societal costs. Preventing depression in this population may therefore lead to better health outcomes for the individual patient and reduced burden on society. Online psychological interventions are innovative and evidence-based modes of healthcare delivery. The objective was-through a user-centered design-to develop a personalized online psychological intervention aiming at preventing depression in patients with atrial fibrillation.
Guided by the Intervention Mapping framework for the development of complex interventions, we used a qualitative design and conducted a series of collaborative workshops with patients (n = 8) with atrial fibrillation.
Through intensive collaboration, we developed the HOPE-AF intervention targeting nine risk factors for depression that were meaningful to patients. It contains four basic modules that give effective tools to handle daily psychological struggles. Furthermore, patients will receive personal risk factors modules. The evidence-based psychological methodology was applied to all modules. Primary lessons learned were (1) engaging patients from the start to ensure the intervention becomes meaningful; (2) using positive phrasing in all patient-related materials to promote motivation; (3) incorporating patients' choice of preference where possible to personalize the intervention.
Based on a user-centered design, the HOPE-AF intervention aiming to prevent depression in patients with AF, was developed. It was confirmed that it is crucial to engage end-users in the development of complex interventions to accommodate their needs and preferences. The Hope-AF intervention will now be tested in a feasibility study.
约30%的房颤患者患有抑郁症。房颤患者的抑郁症与健康状况不佳、健康相关生活质量下降以及社会成本升高有关。因此，预防该人群的抑郁症可能会改善个体患者的健康状况，并减轻社会负担。在线心理干预是创新且基于证据的医疗服务模式。目标是通过以用户为中心的设计，开发一种旨在预防房颤患者抑郁症的个性化在线心理干预。
在用于开发复杂干预措施的干预映射框架的指导下，我们采用定性设计，并与8名房颤患者进行了一系列合作研讨会。
通过深入合作，我们开发了HOPE-AF干预措施，针对对患者有意义的9个抑郁症风险因素。它包含四个基本模块，提供了应对日常心理困扰的有效工具。此外，患者将收到个人风险因素模块。所有模块均应用了基于证据的心理学方法。主要经验教训包括：（1）从一开始就让患者参与进来，以确保干预措施变得有意义；（2）在所有与患者相关的材料中使用积极的措辞以促进积极性；（3）尽可能纳入患者的偏好选择，以使干预措施个性化。
基于以用户为中心的设计，开发了旨在预防房颤患者抑郁症的HOPE-AF干预措施。已证实，让最终用户参与复杂干预措施的开发以满足他们的需求和偏好至关重要。HOPE-AF干预措施现在将在一项可行性研究中进行测试。
