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一名27岁日本女性因可触及及可见的硬化性浅表血栓性静脉炎(蒙多氏病)出现左胸壁疼痛。

A 27-Year-Old Japanese Woman Presenting with Left Chest Wall Pain Due to Palpable and Visible Sclerosing Superficial Thrombophlebitis (Mondor's Disease).

作者信息

Takahashi Yuichi, Deshpande Gautam A, Mine Yuichiro, Saita Mizue, Naito Toshio

机构信息

Department of General Medicine, Juntendo University Faculty of Medicine, Bunkyo, Tokyo, Japan.

出版信息

Am J Case Rep. 2025 Jan 7;26:e945901. doi: 10.12659/AJCR.945901.

DOI:10.12659/AJCR.945901
PMID:39763158
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11725653/
Abstract

BACKGROUND Mondor's disease (MD), or sclerosing superficial thrombophlebitis of the veins of the anterior thoracic wall, is a rare condition of unknown cause that usually involves the superior epigastric vein, producing a visible and palpable Mondor cord. This report describes a 27-year-old Japanese woman presenting with left chest wall pain due to palpable and visible sclerosing superficial thrombophlebitis. CASE REPORT We present the case of a 27-year-old Japanese woman who presented with 8 days of left chest wall and upper abdominal pain. Physical examination revealed a firm, palpable cord in the painful area. Chest wall ultrasound revealed a tubular and anechoic superficial cord. Doppler imaging demonstrated normal blood flow surrounding the cord, with no blood flow within. Computed tomography (CT) revealed a subtle structure beneath the lower left breast skin and without breast or lung involvement. We diagnosed her as having MD, and she was treated with non-steroidal anti-inflammatory drugs (NSAIDs). Her pain gradually improved in 3 weeks and the cord disappeared after approximately 2 months. CONCLUSIONS Mondor's disease can be distressing and painful for patients. Clinicians should be aware of this rare and benign disease when a longitudinal painful cord is found in the torso wall. Pain relief and reassurance are typically adequate until resolution. In addition to ultrasonography, CT is also important for diagnosing MD. This report of a rare diagnosis of MD highlights the importance of accurate and timely diagnosis and investigating the patient to exclude superficial and deep venous thrombotic disease.

摘要

背景 蒙多氏病(MD),即前胸壁静脉硬化性浅静脉炎,是一种病因不明的罕见病症,通常累及腹壁上静脉,形成可看见和触及的蒙多氏条索。本报告描述了一名27岁日本女性,因可触及且可见的硬化性浅静脉炎而出现左胸壁疼痛。病例报告 我们报告一例27岁日本女性,出现左胸壁和上腹部疼痛8天。体格检查发现疼痛区域有一条坚硬、可触及的条索。胸壁超声显示一条管状无回声浅条索。多普勒成像显示条索周围血流正常,内部无血流。计算机断层扫描(CT)显示左乳房下皮肤下方有一细微结构,未累及乳房或肺部。我们诊断她患有MD,给予非甾体抗炎药(NSAIDs)治疗。她的疼痛在3周内逐渐改善,条索在约2个月后消失。结论 蒙多氏病可能给患者带来痛苦。当在躯干壁发现纵向疼痛性条索时,临床医生应意识到这种罕见的良性疾病。在症状消退前,缓解疼痛并给予安慰通常就足够了。除超声检查外,CT对MD的诊断也很重要。这份关于MD罕见诊断的报告强调了准确及时诊断以及对患者进行检查以排除浅静脉和深静脉血栓性疾病的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9bd1/11725653/d447a07e0b72/amjcaserep-26-e945901-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9bd1/11725653/b8f9346a5048/amjcaserep-26-e945901-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9bd1/11725653/21a6d2e28fc7/amjcaserep-26-e945901-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9bd1/11725653/67bcfe551acd/amjcaserep-26-e945901-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9bd1/11725653/d447a07e0b72/amjcaserep-26-e945901-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9bd1/11725653/b8f9346a5048/amjcaserep-26-e945901-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9bd1/11725653/21a6d2e28fc7/amjcaserep-26-e945901-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9bd1/11725653/67bcfe551acd/amjcaserep-26-e945901-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9bd1/11725653/d447a07e0b72/amjcaserep-26-e945901-g004.jpg

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本文引用的文献

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A Smartphone Photograph-assisted Diagnosis of Recurrent Mondor's Disease.智能手机照片辅助诊断复发性蒙多病。
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Mondor's disease of the breast: A cutaneous thromboembolic manifestation of Covid-19?乳房 Mondor 病:Covid-19 的一种皮肤血栓栓塞表现?
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An unusual presentation of penile Mondor's disease in an HIV-positive patient.HIV 阳性患者阴茎Mondor 病的一种不寻常表现。
Ann R Coll Surg Engl. 2022 Nov;104(9):e258-e260. doi: 10.1308/rcsann.2022.0034. Epub 2022 May 31.
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Association of Mondor's disease with oral contraceptive pills.蒙多氏病与口服避孕药的关联。
BMJ Case Rep. 2019 Dec 15;12(12):e232158. doi: 10.1136/bcr-2019-232158.
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Blurred lines between axillary web syndrome and Mondor's disease after breast cancer surgery: A case report.乳腺癌手术后腋网综合征与蒙多氏病之间的界限模糊:一例报告。
Ann Phys Rehabil Med. 2020 Jul;63(4):365-367. doi: 10.1016/j.rehab.2019.04.007. Epub 2019 May 20.
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American Society of Hematology 2018 guidelines for management of venous thromboembolism: venous thromboembolism in the context of pregnancy.美国血液学会 2018 年静脉血栓栓塞症管理指南:妊娠相关静脉血栓栓塞症。
Blood Adv. 2018 Nov 27;2(22):3317-3359. doi: 10.1182/bloodadvances.2018024802.
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Mondor's Disease: A Review of the Literature.蒙多氏病:文献综述
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Mondor's disease - a rare cause of chest pain: a case report.蒙多氏病——胸痛的罕见病因:一例报告
J Med Case Rep. 2018 Jan 9;12(1):4. doi: 10.1186/s13256-017-1530-x.
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Mondor's Disease: Rare case of a painful breast lump in a middle-aged woman.蒙多氏病:中年女性乳房疼痛性肿块的罕见病例。
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