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机器灌注器官保存:2024年美国移植大会亮点

Machine perfusion organ preservation: Highlights from the American transplant congress 2024.

作者信息

Pitchaimuthu Maheswaran, Crochet Carol, Battula Narendra R, Faria Isabella, Martins Paulo N

机构信息

Department of Surgery, Division of Transplantation, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA.

Department of Surgery, University of Texas Medical Branch, Galveston, Texas, USA.

出版信息

Artif Organs. 2025 Feb;49(2):326-331. doi: 10.1111/aor.14923. Epub 2025 Jan 6.

DOI:10.1111/aor.14923
PMID:39763219
Abstract

The American Transplant Congress (ATC) 2024, held in Philadelphia, serves as a vital platform for unveiling new research and clinical experience in organ machine perfusion-a key area in organ transplantation. This year's congress gathered 4652 participants from 49 countries, including top experts, to spotlight innovations in machine perfusion across various organ types, such as the liver, kidney, heart, and lung. A total of 87 abstracts on organ machine perfusion were presented. We selected 39 abstracts that showed advances including new approaches to organ preservation, promising treatments and biomarkers, cellular therapy, and novel research areas. ATC 2024 underscored major advancements in machine perfusion in both experimental and clinical studies and demonstrated its role as a disruptive force in enhancing transplant outcomes and expanding the donor pool, fostering a robust exchange of knowledge on a global scale.

摘要

在美国费城举行的2024年美国移植大会(ATC),是展示器官机器灌注这一器官移植关键领域新研究和临床经验的重要平台。今年的大会汇聚了来自49个国家的4652名参与者,包括顶尖专家,以聚焦各种器官类型(如肝脏、肾脏、心脏和肺)的机器灌注创新。共展示了87篇关于器官机器灌注的摘要。我们挑选了39篇显示有进展的摘要,包括器官保存的新方法、有前景的治疗方法和生物标志物、细胞疗法以及新的研究领域。2024年美国移植大会强调了机器灌注在实验和临床研究中的重大进展,并展示了其作为一种变革力量在提高移植效果和扩大供体库方面的作用,促进了全球范围内强大的知识交流。

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