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慢性中耳炎鼓室成形术中影响听力学结果的因素:一项前瞻性多中心研究。

Factors influencing audiologic outcomes in ossiculoplasty for chronic otitis media: a prospective multicentre study.

作者信息

Fadda Gianluca, Merlino Federico, Cavallo Giovanni, Moglio Simone, Magliulo Giuseppe, Iannella Giannicola, Greco Antonio, Pace Annalisa, De Vito Andrea, Cammaroto Giovanni, Ronsivalle Salvatore, Di Luca Milena, Parisi Federica, Frisina Antonio, Canzi Pietro, Ferlito Salvatore, Maniaci Antonino

机构信息

Department of Otolaryngology, San Luigi Gonzaga Hospital, University of Turin, Orbassano, Italy.

Otolaryngology Service, ASP ENNA, Enna, Italy.

出版信息

Acta Otorhinolaryngol Ital. 2024 Dec;44(6):400-411. doi: 10.14639/0392-100X-N2973.

Abstract

OBJECTIVES

Chronic otitis media (COM) is a prevalent condition affecting auditory function. Ossiculoplasty is a known treatment strategy, but its effectiveness concerning the presence of cholesteatoma has not been extensively studied.

METHODS

We conducted a multicentre study involving 153 patients diagnosed with COM without cholesteatoma (ncCOM) and with cholesteatoma (cCOM). Patients underwent ossiculoplasty, and postoperative hearing outcomes were analysed.

RESULTS

After patient selection, 133 participants were included. Postoperatively, significant improvements in hearing function were observed in both groups, substantiating the role of ossiculoplasty in treatment of COM. However, different outcomes were noted between ncCOM and cCOM. Patients with cCOM demonstrated a slightly lesser degree of hearing improvement post-surgery compared to their ncCOM counterparts.

CONCLUSIONS

Our findings confirm ossiculoplasty as a standard and effective treatment strategy for COM. The presence of cholesteatoma may influence the effectiveness of surgery, underscoring the need for individualised surgical planning. Future research should focus on confirming these results and more comprehensively exploring the impact of cholesteatoma on surgical outcomes.

摘要

目的

慢性中耳炎(COM)是一种影响听觉功能的常见病症。听骨链成形术是一种已知的治疗策略,但其在胆脂瘤存在情况下的有效性尚未得到广泛研究。

方法

我们进行了一项多中心研究,纳入了153例被诊断为无胆脂瘤慢性中耳炎(ncCOM)和有胆脂瘤慢性中耳炎(cCOM)的患者。患者接受了听骨链成形术,并对术后听力结果进行了分析。

结果

经过患者筛选,共纳入133名参与者。术后,两组患者的听力功能均有显著改善,证实了听骨链成形术在COM治疗中的作用。然而,ncCOM和cCOM之间观察到了不同的结果。与ncCOM患者相比,cCOM患者术后听力改善程度略小。

结论

我们的研究结果证实听骨链成形术是COM的一种标准且有效的治疗策略。胆脂瘤的存在可能会影响手术效果,强调了个性化手术规划的必要性。未来的研究应专注于证实这些结果,并更全面地探索胆脂瘤对手术结果的影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/596b/11706519/5c2a6049cb93/aoi-2024-06-400-g001.jpg

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