Jung Da Jung, Son Jigon, Kwon Ha Gyung, Kwon Eunhye, Lee Kyu-Yup
Department of Otorhinolaryngology-Head and Neck Surgery, School of Medicine, Kyungpook National University, 200 Dongdeok-ro, Jung-gu, Daegu, 700-721, Republic of Korea.
Sci Rep. 2025 Feb 10;15(1):4974. doi: 10.1038/s41598-024-84966-0.
Chronic otitis media (COM) is treated medically and/or surgically. Ossiculoplasty for COM with severe-to-profound hearing loss has not been recommended because the severity of hearing loss before surgery is negatively associated with postoperative hearing improvement. Our study assessed the effectiveness of ossiculoplasty for severe-to-profound hearing loss and identified prognostic factors associated with favorable outcomes. We retrospectively reviewed the medical records of 182 patients with severe-to-profound hearing loss who underwent ossiculoplasty with tympanoplasty and mastoidectomy for COM between January 2017 and December 2018. Air conduction, bone conduction, and air-bone gap significantly improved compared to baseline values. Univariate analysis revealed that high ossiculoplasty outcome parameter staging (OOPS) or middle ear risk index (MERI) scores, obstructed Eustachian tube status, or computed tomography (CT) findings with sclerotic mastoid or soft tissue density (STD) of the retrotympanic space were associated with a lower odds ratio for air gain ≥ 20 dB at 12 months postoperatively. Multivariate analysis revealed that a high OOPS score and obstructed Eustachian tube significantly predicted poorer outcomes. In conclusion, ossiculoplasty can be considered for selected patients with COM, such as those with a low OOPS index, aerated middle ear, or no STD of the retrotympanic space on CT, before cochlear implantation even if they had severe-to-profound hearing loss and high bone conduction threshold.
慢性中耳炎(COM)的治疗方式包括药物治疗和/或手术治疗。对于重度至极重度听力损失的COM患者,不建议进行听骨链成形术,因为术前听力损失的严重程度与术后听力改善呈负相关。我们的研究评估了听骨链成形术对重度至极重度听力损失的有效性,并确定了与良好预后相关的预测因素。我们回顾性分析了2017年1月至2018年12月期间182例因COM接受听骨链成形术联合鼓膜成形术和乳突切除术的重度至极重度听力损失患者的病历。与基线值相比,气导、骨导和气骨导间距均有显著改善。单因素分析显示,听骨链成形术结果参数高分期(OOPS)或中耳风险指数(MERI)评分、咽鼓管阻塞状态,或计算机断层扫描(CT)显示硬化性乳突或鼓室后间隙软组织密度(STD)的结果与术后12个月气导增益≥20 dB的较低比值比相关。多因素分析显示,高OOPS评分和咽鼓管阻塞显著预示预后较差。总之,对于某些COM患者,如OOPS指数低、中耳通气良好或CT显示鼓室后间隙无STD的患者,即使他们有重度至极重度听力损失和高骨导阈值,在进行人工耳蜗植入之前,也可以考虑进行听骨链成形术。