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急性缺氧对人胎儿心率的影响。心率变异性增加的意义。

Effect of acute hypoxia on human fetal heart rate. The significance of increased heart rate variability.

作者信息

Thaler I, Timor-Tritsch I E, Blumenfeld Z

出版信息

Acta Obstet Gynecol Scand. 1985;64(1):47-50. doi: 10.3109/00016348509154687.

DOI:10.3109/00016348509154687
PMID:3976376
Abstract

The fetal heart rate response to acute hypoxemia was observed during an accidental drop in oxygen concentration inspired by the mother in labor. There was a marked increase in FHR variability in the early stage of hypoxia and also during the recovery phase. While an increase in fetal heart variability is generally considered to be a normal physiological event, it may also indicate a state of fetal hypoxemia associated with an intact fetal circulation, and should be treated with caution during labor.

摘要

在分娩过程中,因母亲吸入的氧气浓度意外下降而导致急性低氧血症时,观察到了胎儿心率反应。在缺氧早期以及恢复阶段,胎儿心率变异性均显著增加。虽然胎儿心率变异性增加通常被认为是正常的生理事件,但它也可能表明胎儿处于与完整胎儿循环相关的低氧血症状态,在分娩过程中应谨慎处理。

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Increased variability of fetal heart rate during labour: a review of preclinical and clinical studies.分娩过程中胎儿心率变异性增加:临床前和临床研究综述。
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An investigation of fetal behavioural states during maternal sleep in healthy late gestation pregnancy: an observational study.健康晚期妊娠孕妇母体睡眠期间胎儿行为状态的研究:一项观察性研究。
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Effect of maternal position on fetal behavioural state and heart rate variability in healthy late gestation pregnancy.
母亲体位对健康妊娠晚期胎儿行为状态和心率变异性的影响
J Physiol. 2017 Feb 15;595(4):1213-1221. doi: 10.1113/JP273201. Epub 2016 Dec 11.
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Sympathetic neural activation does not mediate heart rate variability during repeated brief umbilical cord occlusions in near-term fetal sheep.在近足月胎儿绵羊反复短暂脐带闭塞期间,交感神经激活并不介导心率变异性。
J Physiol. 2016 Mar 1;594(5):1265-77. doi: 10.1113/JP270125. Epub 2015 May 22.