撤回：生物学黎明时期的结构酶学、系统发育学、分化与符号自反性。
WITHDRAWN: Structural Enzymology, Phylogenetics, Differentiation, and Symbolic Reflexivity at the Dawn of Biology.
作者信息
Carter Charles W, Tang Guo Qing, Patra Sourav Kumar, Betts Laurie, Dieckhaus Henry, Kuhlman Brian, Douglas Jordan, Wills Peter R, Bouckaert Remco, Popovic Milena, Ditzler Mark A
出版信息
bioRxiv. 2025 Jan 14:2024.12.17.628912. doi: 10.1101/2024.12.17.628912.
Abstract
This manuscript was posted without the final consent of all authors. The authors have therefore withdrawn it. The authors do not wish this work to be cited as reference for the project. If you have any questions, please contact the corresponding author, carter@med.unc.edu .
摘要
本手稿未经所有作者最终同意就已发布。因此，作者们撤回了它。作者们不希望这项工作被作为该项目的参考文献引用。如果您有任何问题，请联系通讯作者，邮箱为carter@med.unc.edu 。
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本文引用的文献
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HetMM: A Michaelis-Menten model for non-homogeneous enzyme mixtures.HetMM：一种用于非均相酶混合物的米氏模型。
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Fifty years of Nucleic Acids Research.《核酸研究》五十年
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Enzymic recognition of amino acids drove the evolution of primordial genetic codes.酶对氨基酸的识别驱动了原始遗传密码的进化。
Nucleic Acids Res. 2024 Jan 25;52(2):558-571. doi: 10.1093/nar/gkad1160.
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Domain acquisition by class I aminoacyl-tRNA synthetase urzymes coordinated the catalytic functions of HVGH and KMSKS motifs.I 类氨酰-tRNA 合成酶 urzymes 通过结构域获取，协调 HVGH 和 KMSKS 基序的催化功能。
Nucleic Acids Res. 2023 Aug 25;51(15):8070-8084. doi: 10.1093/nar/gkad590.
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The binding mode of orphan glycyl-tRNA synthetase with tRNA supports the synthetase classification and reveals large domain movements.孤儿甘氨酰-tRNA 合成酶与 tRNA 的结合模式支持合成酶分类，并揭示了大的结构域运动。
Sci Adv. 2023 Feb 10;9(6):eadf1027. doi: 10.1126/sciadv.adf1027. Epub 2023 Feb 8.
6
Multidimensional Phylogenetic Metrics Identify Class I Aminoacyl-tRNA Synthetase Evolutionary Mosaicity and Inter-Modular Coupling.多维系统发育度量指标鉴定 I 类氨酰-tRNA 合成酶的进化镶嵌性和模块间耦合性。
Int J Mol Sci. 2022 Jan 28;23(3):1520. doi: 10.3390/ijms23031520.
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Amino acid activation analysis of primitive aminoacyl-tRNA synthetases encoded by both strands of a single gene using the malachite green assay.利用孔雀绿法对单条基因的两条链编码的原始氨酰-tRNA 合成酶进行氨基酸激活分析。
Biosystems. 2021 Oct;208:104481. doi: 10.1016/j.biosystems.2021.104481. Epub 2021 Jul 8.
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