Du Zhiqiang, Jiang Ying, Shen Yuan, Zhou Qin, Gong Peng, Zhu Haohao
Affiliated Mental Health Center of Jiangnan University, Wuxi Central Rehabilitation Hospital, Wuxi, China.
CNS Neurosci Ther. 2025 Jan;31(1):e70213. doi: 10.1111/cns.70213.
The study found a significant causal relationship between coffee intake and obsessive-compulsive disorder, showing a negative correlation. There was no causal relationship between coffee intake and other mental disorders. The sensitivity analysis test found no pleiotropy affecting the results, and no single nucleotide polymorphism had a major impact on the robustness of the results, indicating that the results are stable and reliable.
该研究发现咖啡摄入量与强迫症之间存在显著的因果关系,呈负相关。咖啡摄入量与其他精神障碍之间不存在因果关系。敏感性分析测试未发现影响结果的多效性,且没有单核苷酸多态性对结果的稳健性有重大影响,表明结果稳定可靠。