Kubota I, Ikeda K, Kanaya T, Yamaki M, Tonooka I, Watanabe Y, Tsuiki K, Yasui S
Am Heart J. 1985 Mar;109(3 Pt 1):464-71. doi: 10.1016/0002-8703(85)90549-6.
In order to determine to what extent left ventriculographic abnormalities can be predicted from ECG changes in myocardial infarction (MI), 87 unipolar ECGs were simultaneously recorded in 22 patients with previous anterior MI with no conduction defects. We adopted a QRS isointegral mapping technique for analyzing body surface mapping data. Particular attention was given to the area where the QRS time-integral value was less than the lower limit (mean minus two standard deviations) of the normal, and this area was designated as the departure area. Left ventricular wall motion was assessed by left ventriculography and correlated with the departure area. The departure area demonstrated a close correlation with the left ventricular ejection fraction (r = -0.93) and the extent of asynergy (r = 0.74). It is suggested that the departure area reflects the loss of electromotive force due to MI. We conclude from this study that the QRS isointegral map is a useful method for evaluating left ventricular function in patients with anterior MI.
为了确定心肌梗死（MI）时心电图变化能在多大程度上预测左心室造影异常，我们对22例既往有前壁心肌梗死且无传导缺陷的患者同步记录了87份单极心电图。我们采用QRS等积分映射技术分析体表映射数据。特别关注QRS时间积分值低于正常下限（平均值减去两个标准差）的区域，该区域被指定为背离区。通过左心室造影评估左心室壁运动，并将其与背离区相关联。背离区与左心室射血分数（r = -0.93）和协同失调程度（r = 0.74）密切相关。提示背离区反映了心肌梗死导致的电动势丧失。我们从这项研究得出结论，QRS等积分图是评估前壁心肌梗死患者左心室功能的一种有用方法。
