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经椎间孔腰椎内镜下椎间盘切除术:类风湿性关节炎患者腰椎间盘突出症治疗的一种新选择?

Transforaminal Lumbar Endoscopic Discectomy: A Novel Alternative for Management of Lumbar Disc Herniation in Patients With Rheumatoid Arthritis?

作者信息

Kapetanakis Stylianos, Chaniotakis Constantinos, Tsioulas Paschalis, Gkantsinikoudis Nikolaos

机构信息

Spine Department and Deformities, Interbalkan European Medical Center, Thessaloniki, Greece.

Department of Minimally Invasive and Endoscopic Spine Surgery, Athens Medical Center, Athens, Greece.

出版信息

Neurospine. 2024 Dec;21(4):1210-1218. doi: 10.14245/ns.2448634.317. Epub 2024 Dec 31.

Abstract

OBJECTIVE

Lumbar disc herniation (LDH) represents an increasingly encountered condition in patients with rheumatoid arthritis (RA). The aim of the present study is to assess the progress of health-related quality of life following transforaminal endoscopic lumbar discectomy (TELD) for LDH in patients suffering from RA.

METHODS

Seventy-four patients, scheduled to undergo elective TELD for LDH, were prospectively enrolled in the study. Group A included 36 otherwise healthy individuals and group B 38 patients complementarily diagnosed with RA according to the 2010 ACR/EULAR (American College of Rheumatology/European League Against Rheumatism) criteria. The Medical Outcomes Study 36-item Short Form health survey (SF-36) was selected for the outcome assessment at baseline and postoperatively, at selected intervals at 6 weeks, 3, 6, and 12 months postoperatively.

RESULTS

Group A presented statistically significantly higher scores in all SF-36 domains and all selected intervals (p<0.001), except for mental health parameter. All aspects of SF-36 questionnaire significantly improved postoperatively (p<0.001) and in each group independently. Nevertheless, the absolute improvement between consecutive time intervals did not differ significantly between the 2 groups.

CONCLUSION

Patients diagnosed with RA who undergo TELD for LDH demonstrate statistically significant improvement in their health status, as measured by SF-36 questionnaire, one year after the procedure. This improvement is comparable with normal individuals.

摘要

目的

腰椎间盘突出症(LDH)在类风湿关节炎(RA)患者中越来越常见。本研究的目的是评估经椎间孔内镜下腰椎间盘切除术(TELD)治疗RA患者LDH后健康相关生活质量的进展。

方法

前瞻性纳入74例计划接受择期TELD治疗LDH的患者。A组包括36名健康个体,B组包括38例根据2010年美国风湿病学会/欧洲抗风湿病联盟(ACR/EULAR)标准确诊为RA的患者。在基线、术后以及术后6周、3个月、6个月和12个月的选定时间间隔,选用医学结局研究36项简表健康调查(SF-36)进行结局评估。

结果

除心理健康参数外,A组在所有SF-36领域和所有选定时间间隔的得分均具有统计学显著差异(p<0.001)。SF-36问卷的所有方面在术后均有显著改善(p<0.001),且在每组中均独立存在。然而,两组在连续时间间隔之间的绝对改善差异不显著。

结论

通过SF-36问卷测量,接受TELD治疗LDH的RA患者在术后一年健康状况有统计学显著改善。这种改善与正常个体相当。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/50fc/11744524/4de9017ce404/ns-2448634-317f1.jpg

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