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局麻下单侧入路椎间孔镜与椎板间入路内镜下腰椎间盘切除术治疗 L5/S1 椎间盘突出症的随机对照研究

Transforaminal Versus Interlaminar Approach of Full-Endoscopic Lumbar Discectomy Under Local Anesthesia for L5/S1 Disc Herniation: A Randomized Controlled Trial.

机构信息

The Department of Orthopedics, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China.

The Department of Operating Nursing, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China.

出版信息

Pain Physician. 2022 Nov;25(8):E1191-E1198.

Abstract

BACKGROUND

Local anesthesia is feasible for both transforaminal and interlaminar approaches in percutaneous endoscopic lumbar discectomy (PELD). However, the optimal approach for PELD has not yet been established at the L5/S1 segment under local anesthesia with 1% lidocaine.

OBJECTIVES

In this study, we compared the transforaminal approach with the interlaminar approach of PELD under local anesthesia for L5/S1 disc herniation (DH).

STUDY DESIGN

This was a prospective randomized clinical trial.

METHODS

From January 2019 to March 2020, 91 consecutive patients with L5/S1 DH who planned to undergo PELD in our unit were randomized to the transforaminal endoscopic lumbar discectomy (TELD, n = 46) or interlaminar endoscopic lumbar discectomy (IELD, n = 45). Both procedures were performed under local anesthesia with 1% lidocaine. The clinical outcomes were assessed as the Visual Analog Scale (VAS) score, Oswestry Disability Index (ODI) score, and modified MacNab criteria. Patient satisfaction surveys and surgical complications were also recorded and analyzed.

RESULTS

Compared to the IELD group, the TELD group had a shorter operative time and postoperative bed rest time (P < 0.001) but a longer radiation time (P < 0.001) and lower VAS scores for intraoperative back pain (P < 0.001) and leg pain (P < 0.001). At the postoperative follow-up, there were no significant differences between the 2 groups in the VAS scores, ODI scores, or modified MacNab criteria. The surveys showed a significantly higher satisfaction rate in the TELD group than in the IELD group (P = 0.014). Six patients in the IELD group (13.3%) needed extra intravenous injections of sufentanil because of intense pain during the procedure. In the IELD group, there were 2 cases of neuropathic pain after surgery.

LIMITATIONS

Due to the study was included in a single spine center with a relatively small population and its relatively short-term follow-up, the study is not generalizable.

CONCLUSIONS

Both TELD and IELD can provide good clinical outcomes for L5/S1 DH under local anesthesia with 1% lidocaine. TELD was superior to IELD in terms of surgical-related experience and complications.

摘要

背景

局部麻醉可用于经皮内镜腰椎间盘切除术(PELD)的经椎间孔入路和经椎间孔入路。然而,在局部麻醉下使用 1%利多卡因时,对于 L5/S1 节段,尚未确定 PELD 的最佳入路方法。

目的

本研究比较了局部麻醉下经皮内镜腰椎间盘切除术(PELD)的经椎间孔入路与经椎间孔入路治疗 L5/S1 椎间盘突出症(DH)的疗效。

研究设计

这是一项前瞻性随机临床试验。

方法

2019 年 1 月至 2020 年 3 月,我院拟行 PELD 治疗的 91 例 L5/S1DH 连续患者随机分为经皮椎间孔内窥镜腰椎间盘切除术(TELD,n=46)或经皮椎间孔内窥镜腰椎间盘切除术(IEL,n=45)。两种手术均在局部麻醉下使用 1%利多卡因进行。采用视觉模拟评分(VAS)、Oswestry 功能障碍指数(ODI)评分和改良 MacNab 标准评估临床疗效。还记录和分析了患者满意度调查和手术并发症。

结果

与 IELD 组相比,TELD 组手术时间和术后卧床时间较短(P<0.001),但放射时间较长(P<0.001),术中腰痛(P<0.001)和腿痛(P<0.001)的 VAS 评分较低。术后随访时,两组 VAS 评分、ODI 评分或改良 MacNab 标准无显著性差异。问卷调查显示 TELD 组满意度明显高于 IELD 组(P=0.014)。IELD 组 6 例(13.3%)患者因术中疼痛剧烈需额外静脉注射舒芬太尼。IELD 组术后有 2 例出现神经痛。

局限性

由于该研究纳入了一个相对较小的人群和相对较短的随访期,因此仅在一个脊柱中心进行,研究结果不具有普遍性。

结论

在局部麻醉下使用 1%利多卡因时,TELD 和 IELD 均可为 L5/S1DH 提供良好的临床疗效。TELD 在手术相关经验和并发症方面优于 IELD。

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