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双极射频热疗与经尿道前列腺切除术治疗良性前列腺梗阻所致储尿期症状的临床疗效比较研究

A Comparative Study on the Clinical Outcomes of Bipolar Radiofrequency Thermotherapy Versus Transurethral Resection of the Prostate in Storage Symptoms Associated With Benign Prostatic Obstruction.

作者信息

Yuce Ahmet, Benli Erdal, Basar Dilek, Yazıcı İbrahim, Çırakoğlu Abdullah, Nalbant İsmail

机构信息

Department of Urology, Ordu University, Faculty of Medicine, Ordu, Turkey.

Department of Pediatric Surgery, Trabzon Kanuni Training and Research Hospital, Trabzon, Turkey.

出版信息

Int Neurourol J. 2024 Dec;28(4):285-293. doi: 10.5213/inj.2346184.092. Epub 2024 Dec 31.

Abstract

PURPOSE

The aim of the study was to compare the results of radiofrequency (RF) thermotherapy and transurethral resection of the prostate (TURP) in patients who required benign prostatic obstruction (BPO) surgery and had storage symptoms.

METHODS

The results of patients who had undergone TURP and RF thermotherapy procedures between December 2019 and 2022 were compared before and after the procedure. Patients' International Prostate Symptom Scores, maximum flow rate (Qmax), postvoiding residues, and overactive bladder validated 8 scores (OAB-V8) at 3 and 6 months were analyzed.

RESULTS

While the preprocedural OAB-V8 in the RF thermotherapy group was 25.85, this score decreased to 18.12 (P<0.001) at the postprocedural 3rd month and 16.42 (P<0.001) at the postprocedural 6th month. While the preprocedural OAB-V8 score in TURP group was 23.26, it decreased to 20.17 (P<0.001) at the postprocedural 3rd month and 19.84 at the postprocedural 6th month, and there was no significant difference between the 3rd-month and 6th-month values (P=0.328). The proportion of de crease in the OAB-V8 scores was 30% at the 3rd month and 36% at the 6th month in the RF thermotherapy group, whereas it was 13% at the 3rd month and 15% at the 6th month in TURP group.

CONCLUSION

It was determined that RF thermotherapy was 2.35 times more effective than TURP on OAB-V8 scores. In addition to its acceptable effect on Qmax, its continued effect on storage symptoms at 6 months may be a significant advantage over the TURP. As a minimally invasive method, RF thermotherapy can be offered as a suitable option for BPO patients with storage symptoms.

摘要

目的

本研究旨在比较射频(RF)热疗与经尿道前列腺切除术(TURP)对需要进行良性前列腺梗阻(BPO)手术且有储尿期症状患者的治疗效果。

方法

比较2019年12月至2022年期间接受TURP和RF热疗手术患者在手术前后的情况。分析患者的国际前列腺症状评分、最大尿流率(Qmax)、残余尿量以及术后3个月和6个月时的膀胱过度活动症有效8项评分(OAB-V8)。

结果

RF热疗组术前OAB-V8评分为25.85,术后第3个月降至18.12(P<0.001),术后第6个月降至16.42(P<0.001)。TURP组术前OAB-V8评分为23.26,术后第3个月降至20.17(P<0.001),术后第6个月为19.84,第3个月和第6个月的值之间无显著差异(P=0.328)。RF热疗组OAB-V8评分在第3个月下降比例为30%,第6个月为36%;而TURP组第3个月为13%,第6个月为15%。

结论

研究确定RF热疗在OAB-V8评分上比TURP有效2.35倍。除了对Qmax有可接受的效果外,其在6个月时对储尿期症状的持续作用可能是优于TURP的显著优势。作为一种微创方法,RF热疗可作为有储尿期症状的BPO患者的合适选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5230/11710952/2ed100f9e660/inj-2346184-092f1.jpg

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