Pan Yu, Yan Zechen, Zhuang Chen, Chen Wenhuan, Guo Weijie, Su Hui, Liu Luyao, Zhuang Rujie, Guo Wenxuan
Department of Orthopaedics, The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Traditional Chinese Medicine), Hangzhou, Zhejiang, China.
The First School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China.
Foot Ankle Surg. 2025 Jul;31(5):384-391. doi: 10.1016/j.fas.2025.01.004. Epub 2025 Jan 3.
The optimal treatment of Osteochondral lesion of the talus (OLT) for subchondral bone cysts (SBCs) has not been finalized. The purpose of this systematic review and meta-analysis was to define whether OLT with small SBCs will affect the clinical outcomes of OLTs after arthroscopic microfracture.
We searched the Embase, Cochrane Library and PubMed databases up to May 13, 2024 for eligible comparative studies. The methodological index for non-randomized studies (MINORS) were used for assessing the methodological quality. The Review Manager 5.4 software was applied to perform the statistical analysis.
A total of 4 studies involving 257 patients were included in this meta-analysis. No significant difference was noted in American Orthopaedic Foot and Ankle Society (AOFAS) Ankle-Hindfoot Scale, the improvement of Foot and Ankle Ability Measure- Activities of Daily Life (FAAM-ADL) and Foot and Ankle Ability Measure (FAAM-SP), Tegner Score and Visual Analogue Scale (VAS) between the cyst and noncyst group. The noncyst group was statistically significant in term of FAAM-ADL and FAAM-SP. Radiological outcomes in the cyst group had improved after arthroscopic microfracture.
Based on the results of the present study, there are no clinical differences with the technique of bone marrow stimulation between simple and cystic ostechondral lesions of talus with depth smaller than 5-6 mm, with respect to the medial part of talus and referring to age younger than 40 years old.
Level 3.
距骨骨软骨损伤(OLT)合并软骨下骨囊肿(SBCs)的最佳治疗方案尚未确定。本系统评价和荟萃分析的目的是确定小SBCs的OLT是否会影响关节镜下微骨折术后OLT的临床疗效。
检索截至2024年5月13日的Embase、Cochrane图书馆和PubMed数据库,查找符合条件的比较研究。采用非随机研究方法学指标(MINORS)评估方法学质量。应用Review Manager 5.4软件进行统计分析。
本荟萃分析共纳入4项研究,涉及257例患者。囊肿组和非囊肿组在 American Orthopaedic Foot and Ankle Society(AOFAS)踝-后足评分、足踝功能测量-日常生活活动(FAAM-ADL)和足踝功能测量(FAAM-SP)改善情况、Tegner评分和视觉模拟量表(VAS)方面均无显著差异。非囊肿组在FAAM-ADL和FAAM-SP方面具有统计学意义。关节镜下微骨折术后囊肿组的影像学结果有所改善。
基于本研究结果,对于距骨内侧部分且年龄小于40岁、深度小于5-6mm的单纯性和囊性距骨骨软骨损伤,骨髓刺激技术在临床疗效上无差异。
3级。