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基因组学时代牙科的靶向基因教育

Targeted Genetic Education in Dentistry in the Era of Genomics.

作者信息

Asa'ad Farah, Nørremølle Anne, Khan Qalbi, Larsson Lena, Tommerup Niels, Hermann Nuno Vibe, Silahtaroglu Asli

机构信息

Department of Oral Biochemistry, Institute of Odontology, The Sahlgrenska Academy at University of Gothenburg, P.O. Box 450, SE 405 30 Göteborg, Sweden.

Department of Cellular and Molecular Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3, DK-2200 Copenhagen, Denmark.

出版信息

Genes (Basel). 2024 Nov 22;15(12):1499. doi: 10.3390/genes15121499.

Abstract

The growing body of knowledge on the human genome and its variants points towards the significance of genetic factors in oral health and disease. Since the dental curricula have historically prioritized clinically oriented subjects, this focus has resulted in insufficient coverage of genetics. To leverage this knowledge in patient care, dental education must equip students with an understanding of the principles of genetics. : We have established "Genetic Educators Network in Dentistry" (GEN-Dent) to identify common concerns regarding genetics in dental education and work for a greater emphasis on genetics in future dental programs to make sure that professionals in dentistry are well-prepared to navigate the complexities of the evolving "human genome era". Here, GEN-Dent proposes specific learning goals for medical genetics in dentistry and provides supporting teaching material addressing each learning goal. The five life-like case studies exemplify different dental conditions and introduce important concepts of genetics, inspiring other educators. : Opportunities in Scandinavian countries can be an advantage in increasing global awareness of the importance of genetics in dentistry. The integration of genetics into dental education not only aims to improve patient care but also seeks to inspire a new generation of basic scientists with clinical backgrounds in dentistry. We expect that using life-like patient cases will significantly motivate dental students when learning medical genetics.

摘要

关于人类基因组及其变异的知识体系不断发展,这表明遗传因素在口腔健康和疾病中具有重要意义。由于牙科课程历来优先关注临床导向的学科,这种重点导致对遗传学的覆盖不足。为了在患者护理中利用这些知识,牙科教育必须让学生了解遗传学原理。我们已经建立了“牙科遗传教育者网络”(GEN-Dent),以确定牙科教育中关于遗传学的共同关注点,并努力在未来的牙科课程中更加强调遗传学,以确保牙科专业人员做好充分准备,应对不断发展的“人类基因组时代”的复杂性。在此,GEN-Dent提出了牙科医学遗传学的具体学习目标,并提供针对每个学习目标的辅助教学材料。这五个逼真的案例研究例证了不同的口腔疾病,并引入了重要的遗传学概念,激励其他教育工作者。斯堪的纳维亚国家的机会可能有助于提高全球对遗传学在牙科领域重要性的认识。将遗传学融入牙科教育不仅旨在改善患者护理,还旨在激励新一代具有牙科临床背景的基础科学家。我们预计,使用逼真的患者案例将极大地激发牙科学生学习医学遗传学的积极性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f55e/11675337/bc76e96e5a8e/genes-15-01499-g001a.jpg

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