Wagner D K, Varkey B, Sheth N K, DaMert G J
Am J Med. 1985 Mar;78(3):518-22. doi: 10.1016/0002-9343(85)90349-3.
An aspergilloma developed in a lung cyst in a 53-year-old man. Aspergillus infection then contiguously spread to the epidural space, causing an abscess, vertebral destruction, and paraplegia at the level of T4. Chronic alcoholism, liver cirrhosis, and corticosteroid treatment may have been predisposing factors in this patient. Although Aspergillus epidural abscess has been described infrequently, this complication has not been described in association with an aspergilloma. Symptoms, signs, or roentgenographic or laboratory findings suggestive of vertebral or meningeal pathologic lesions in patients with aspergilloma should alert the physician to the possibility of contiguous spread of infection.
一名53岁男性的肺囊肿内发生了曲菌球。随后,曲霉菌感染连续蔓延至硬膜外间隙,导致T4水平的脓肿、椎体破坏和截瘫。慢性酒精中毒、肝硬化和皮质类固醇治疗可能是该患者的易感因素。虽然曲霉菌性硬膜外脓肿的报道较少,但这种并发症尚未见与曲菌球相关的描述。曲菌球患者出现提示椎体或脑膜病理病变的症状、体征、影像学或实验室检查结果,应提醒医生注意感染连续蔓延的可能性。