Hecht J T, Nelson F W, Butler I J, Horton W A, Scott C I, Wassman E R, Mehringer C M, Rimoin D L, Pauli R M
Am J Med Genet. 1985 Feb;20(2):355-60. doi: 10.1002/ajmg.1320200219.
Computerized tomographic dimensions of the foramen magnum of 63 achondroplastic individuals were compared to standards established for nonachondroplastic individuals. The size of the foramen magnum in patients with achondroplasia was small at all ages, particularly in those with serious neurologic problems. The data suggest that measurement of the foramen magnum may identify achondroplastic individuals at high risk of developing neurologic complications.
将63例软骨发育不全个体的枕骨大孔的计算机断层扫描尺寸与为非软骨发育不全个体制定的标准进行了比较。软骨发育不全患者的枕骨大孔尺寸在所有年龄段都较小，尤其是那些有严重神经问题的患者。数据表明，测量枕骨大孔可能有助于识别有发生神经并发症高风险的软骨发育不全个体。
