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胰岛素抵抗伴高胰岛素血症作为心力衰竭发生和恶化的原因

Insulin Resistance with Associated Hyperinsulinemia as a Cause of the Development and Worsening of Heart Failure.

作者信息

Attanasio Umberto, Mercurio Valentina, Fazio Serafino

机构信息

Department of Translational Medical Sciences, Federico II University, 80131 Naples, Italy.

Department of Internal Medicine, School of Medicine, Federico II University, 80131 Naples, Italy.

出版信息

Biomedicines. 2024 Dec 19;12(12):2890. doi: 10.3390/biomedicines12122890.

Abstract

Despite the considerable progress that has been made with regard to the prevention and treatment of cardiovascular diseases, heart failure (HF) remains a particularly important cause of recurring hospitalizations, with relevant social and healthcare costs, and it is a significant cause of mortality; as such, there is a need for continuous efforts to improve our understanding of its complex pathophysiology and refine relevant therapeutic strategies [...].

摘要

尽管在心血管疾病的预防和治疗方面已经取得了相当大的进展,但心力衰竭(HF)仍然是再次住院的一个特别重要的原因,伴随着相关的社会和医疗成本,并且是一个重要的死亡原因;因此,需要持续努力以增进我们对其复杂病理生理学的理解并完善相关治疗策略[……]。

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