Toader Corneliu, Brehar Felix Mircea, Radoi Mugurel Petrinel, Covache-Busuioc Razvan Adrian, Serban Matei, Ciurea Alexandru Vladimir, Dobrin Nicolaie
Department of Neurosurgery, "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Department of Vascular Neurosurgery, National Institute of Neurology and Neurovascular Diseases, 077160 Bucharest, Romania.
J Clin Med. 2024 Dec 10;13(24):7494. doi: 10.3390/jcm13247494.
Cerebral arteriovenous malformations (AVMs) are rare but complex vascular anomalies, particularly challenging when located in eloquent regions such as the corpus callosum and post-central gyrus. This report aims to highlight the management and outcomes of a 41-year-old female patient with a hemorrhagic AVM in these critical areas, emphasizing the importance of early surgical intervention and advanced imaging techniques. The patient presented with a right-sided tonic-clonic seizure and expressive aphasia, prompting imaging that revealed a complex AVM with deep venous drainage and arterial supply from the anterior cerebral artery. A multidisciplinary team performed microsurgical resection via a left parasagittal fronto-parietal craniotomy. The surgical approach prioritized hematoma evacuation followed by a stepwise dissection of the AVM nidus under intraoperative monitoring. Complete resection of the AVM was confirmed through postoperative angiographic and CT imaging. The patient showed stable recovery over 15 months, with no recurrence or new neurological deficits. This case demonstrates the critical role of advanced imaging, intraoperative strategies, and a multidisciplinary approach in achieving successful outcomes. Microsurgical resection remains the gold standard for AVMs in eloquent and deep-seated brain regions. Early diagnosis and tailored surgical interventions are crucial for managing these high-risk cases. This case underscores the importance of integrating advanced imaging, strategic surgical planning, and intraoperative monitoring to minimize complications and optimize long-term recovery.
脑动静脉畸形(AVM)虽罕见但属复杂的血管异常,当位于胼胝体和中央后回等功能区时,治疗极具挑战性。本报告旨在强调一名41岁女性患者在这些关键区域发生出血性AVM的治疗及结果,凸显早期手术干预和先进成像技术的重要性。该患者出现右侧强直阵挛性癫痫发作和表达性失语,影像学检查发现一个复杂的AVM,有深部静脉引流且由大脑前动脉供血。一个多学科团队通过左矢状旁额顶开颅术进行了显微手术切除。手术方法优先进行血肿清除,然后在术中监测下逐步分离AVM病灶。术后血管造影和CT成像证实AVM已完全切除。患者在15个月内恢复稳定,无复发或新的神经功能缺损。该病例表明先进成像、术中策略和多学科方法在取得成功结果中发挥的关键作用。显微手术切除仍是功能区和深部脑区AVM的金标准。早期诊断和量身定制的手术干预对于处理这些高风险病例至关重要。该病例强调了整合先进成像、战略手术规划和术中监测以尽量减少并发症并优化长期恢复的重要性。