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鼓膜术前电诱发听觉晚期反应(TympEALR)作为人工耳蜗植入候选者中使用麻醉进行经鼓膜测试的替代方法。

Tympanic Pre-Operative Electrically Evoked Auditory Late Response (TympEALR) as an Alternative to Trans-Tympanic Tests Using Anesthesia in Cochlear Implant Candidacy.

作者信息

Polterauer Daniel, Neuling Maike, Simon Florian

机构信息

Section Cochlear Implantation, Department of Otorhinolaryngology, University Hospital of Munich (LMU), 81377 Munich, Germany.

出版信息

J Clin Med. 2024 Dec 12;13(24):7573. doi: 10.3390/jcm13247573.

Abstract

: Before a cochlear implant is considered, patients undergo various audiological tests to assess their suitability. One key test measures the auditory brainstem response (ABR) to acoustic stimuli. However, in some cases, even with maximum sound stimulation, no response is detected. : The promontory test involves electrical stimulation near the auditory nerve, allowing patients to associate the sensation. Ideally, the electrode is placed in the middle ear after opening the eardrum. This method, along with trans-tympanic electrically evoked ABR in local anesthesia (LA-TT-EABR) and the cortical equivalent (LA-TT-EALR), helps assess the auditory nerve's existence and excitability. The TympEALR test, utilizing a "tympanic LA-TT-EALR", provides an alternative measurement. Previous research has shown the possibility of deriving brainstem and cortical potentials through trans-tympanic electrical stimulation, allowing for objective assessment of the auditory nerve's integrity and potentially objectifying patient sensations. Sixteen patients have been tested using TympEALR. In seven of these, we found a positive response. The morphology was similar to other electrically evoked cortical auditory responses (EALR), e.g., using cochlear implants or trans-tympanic stimulation electrodes. We observed a higher influence of electrical artifacts than in other EALRs. : TympEALR showed positive results in nearly half of the study participants, potentially avoiding invasive procedures. TympEALR can be a valuable alternative to trans-tympanic methods. More research is needed to determine if a negative result suggests against cochlear implantation.

摘要

在考虑植入人工耳蜗之前,患者要接受各种听力学测试以评估其适用性。一项关键测试是测量对声音刺激的听觉脑干反应(ABR)。然而,在某些情况下,即使给予最大声音刺激,也检测不到反应。

岬部测试涉及在听神经附近进行电刺激,让患者将这种感觉联系起来。理想情况下,在打开鼓膜后将电极置于中耳。这种方法,连同局部麻醉下经鼓膜电诱发ABR(LA-TT-EABR)和皮质等效物(LA-TT-EALR),有助于评估听神经的存在和兴奋性。TympEALR测试利用“鼓膜LA-TT-EALR”提供了另一种测量方法。先前的研究表明,通过经鼓膜电刺激有可能引出脑干和皮质电位,从而能够客观评估听神经的完整性,并有可能使患者的感觉客观化。已有16名患者接受了TympEALR测试。其中7名患者有阳性反应。其形态与其他电诱发皮质听觉反应(EALR)相似,例如使用人工耳蜗或经鼓膜刺激电极时的反应。我们观察到,与其他EALR相比,电伪迹的影响更大。

TympEALR在近一半的研究参与者中显示出阳性结果,有可能避免侵入性手术。TympEALR可能是经鼓膜方法的一种有价值的替代方法。需要更多研究来确定阴性结果是否表明不适合植入人工耳蜗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db12/11728447/5d5834820cc1/jcm-13-07573-g001.jpg

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