Wang Kaiya, Yan Kejia, Liu Qian, Wang Zhiyao, Hu Xiao-Yu
College of Materials Science and Technology, Nanjing University of Aeronautics and Astronautics, Nanjing 211106, China.
College of Chemistry and Materials, Jiangxi Normal University, Nanchang 330022, China.
Molecules. 2024 Dec 11;29(24):5854. doi: 10.3390/molecules29245854.
The advancement of synthetic host-guest chemistry has played a pivotal role in exploring and quantifying weak non-covalent interactions, unraveling the intricacies of molecular recognition in both chemical and biological systems. Macrocycles, particularly calix[4]resorcinarene-based cavitands, have demonstrated significant utility in receptor design, facilitating the creation of intricately organized architectures. Within the realm of macrocycles, these cavitands stand out as privileged scaffolds owing to their synthetic adaptability, excellent topological structures, and unique recognition properties. So far, extensive investigations have been conducted on various applications of calix[4]resorcinarene-based cavitands. In this review, we will elaborate on their diverse functions, including catalysis, separation and purification, polymeric materials, sensing, battery materials, as well as drug delivery. This review aims to provide a holistic understanding of the multifaceted roles of calix[4]resorcinarene-based cavitands across various applications, shedding light on their contributions to advancing the field of supramolecular chemistry.
合成主客体化学的发展在探索和量化弱非共价相互作用、揭示化学和生物系统中分子识别的复杂性方面发挥了关键作用。大环化合物，特别是基于杯[4]间苯二酚芳烃的穴状配体，在受体设计中显示出显著的实用性，有助于构建复杂有序的结构。在大环化合物领域，这些穴状配体因其合成适应性、优异的拓扑结构和独特的识别特性而成为具有优势的骨架。到目前为止，人们已经对基于杯[4]间苯二酚芳烃的穴状配体的各种应用进行了广泛研究。在这篇综述中，我们将详细阐述它们的多种功能，包括催化、分离与纯化、高分子材料、传感、电池材料以及药物递送。这篇综述旨在全面了解基于杯[4]间苯二酚芳烃的穴状配体在各种应用中的多方面作用，阐明它们对推动超分子化学领域发展的贡献。
