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从新冠疫情中汲取的抗击抗菌药物耐药性的经验——中国香港的经历

Lessons Learned from COVID-19 Pandemic in Combating Antimicrobial Resistance-Experience of Hong Kong, China.

作者信息

Ma Edmond Siu-Keung, Wong Shuk-Ching, Cheng Vincent Chi-Chung, Chen Hong, Wu Peng

机构信息

Infection Control Branch, Centre for Health Protection, Department of Health, Hong Kong, China.

Infection Control Team, Queen Mary Hospital, Hong Kong West Cluster, Hong Kong, China.

出版信息

Microorganisms. 2024 Dec 19;12(12):2635. doi: 10.3390/microorganisms12122635.

Abstract

The world has gone through the COVID-19 pandemic and has now returned to normalcy. We reviewed the strategies and public health actions conducted in Hong Kong during the COVID-19 pandemic, and reflected on the lessons learned, which are potentially useful in the fight against antimicrobial resistance (AMR). We recommended extending wastewater surveillance for AMR, apart from SARS-CoV2. We suggested exploring the use of rapid tests in outpatients to aid clinical diagnosis and reduce antibiotic use for viral infections. Stringent infection control measures are crucial to prevent nosocomial transmission of resistant microorganisms, such as vancomycin-resistant enterococci and carbapenemase-producing in hospitals and in elderly homes. Taking COVID-19 experiences as a reference, transparent data, the prompt dissemination of information, and strategic risk communication should be adopted to maintain sustained behavioral changes in AMR. We also encouraged the adoption of information technology, artificial intelligence, and machine learning in antimicrobial stewardship programs. We also discussed the potential merits and limitations of these strategies. The lessons learned from the COVID-19 pandemic may provide insights into the long battle against AMR.

摘要

世界经历了新冠疫情,现已恢复正常。我们回顾了香港在新冠疫情期间采取的策略和公共卫生行动,并反思了从中吸取的教训,这些教训可能对抗击抗菌药物耐药性(AMR)有用。我们建议除了对严重急性呼吸综合征冠状病毒2(SARS-CoV2)进行监测外,还应扩大对AMR的废水监测。我们建议探索在门诊患者中使用快速检测,以辅助临床诊断并减少病毒感染的抗生素使用。严格的感染控制措施对于预防医院和养老院中耐万古霉素肠球菌和产碳青霉烯酶等耐药微生物的医院内传播至关重要。以新冠疫情的经验为参考,应采用透明数据、及时传播信息和进行战略风险沟通,以维持AMR方面持续的行为改变。我们还鼓励在抗菌药物管理计划中采用信息技术、人工智能和机器学习。我们还讨论了这些策略的潜在优点和局限性。从新冠疫情中吸取的教训可能为抗击AMR的长期斗争提供见解。

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